Alberts W M, Williams J H, Ramsdell J W
Ann Allergy. 1986 Aug;57(2):107-9.
Acid-base abnormalities in adults with acute asthma are highly variable. The major abnormalities have been attributed to changes in PaCO2 secondary to altered alveolar ventilation. Primary metabolic alterations have been thought to be rare in adults. The frequency of metabolic acidosis in acute asthma was reevaluated by way of a review of the medical records of 164 hospitalizations involving 109 adults. The hydrogen ion concentration varied widely and in 27 of 164 episodes (16.5%) the arterial pH was lower than expected for the measured PaCO2. We conclude that the presenting acid-base status of adults with acute asthma is highly variable and metabolic acidosis is not an infrequent finding.
成年急性哮喘患者的酸碱异常情况变化很大。主要异常归因于肺泡通气改变继发的动脉血二氧化碳分压（PaCO2）变化。成人原发性代谢改变被认为较为罕见。通过回顾109名成人的164次住院病历，重新评估了急性哮喘患者代谢性酸中毒的发生率。氢离子浓度变化很大，在164次发作中有27次（16.5%）动脉血pH值低于根据测得的PaCO2预期的值。我们得出结论，成年急性哮喘患者的初始酸碱状态变化很大，代谢性酸中毒并不罕见。
