基于嗜酸性粒细胞炎症的鼻息肉慢性鼻-鼻窦炎分类
[Classification of chronic rhinosinusitis with nasal polyps based on eosinophilic inflammation].
作者信息
Pan L, Liu Z
机构信息
Department of Otorhinolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
出版信息
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Mar 7;54(3):222-226. doi: 10.3760/cma.j.issn.1673-0860.2019.03.013.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disorder characterized by chronic sinonasal mucosal inflammation. CRSwNP can be subdivided into two types based on eosinophilic inflammation: eosinophilic CRSwNP (Eos CRSwNP) and non-eosinophilic CRSwNP (Non-Eos CRSwNP). Eos CRSwNP and Non-Eos CRSwNP demonstrate distinct clinical manifestations, treatment outcomes, and cellular and immunopathologic characteristics. However, currently, there is no unified and generally accepted standard to define the Eos CRSwNP. The aim of this review is to compare the advantages and disadvantages of current methods used to classify Eos CRSwNP, in order to lay foundation for further study.
伴鼻息肉的慢性鼻-鼻窦炎（CRSwNP）是一种以慢性鼻窦黏膜炎症为特征的异质性疾病。根据嗜酸性粒细胞炎症，CRSwNP可分为两种类型：嗜酸性粒细胞性CRSwNP（Eos CRSwNP）和非嗜酸性粒细胞性CRSwNP（Non-Eos CRSwNP）。Eos CRSwNP和Non-Eos CRSwNP表现出不同的临床表现、治疗效果以及细胞和免疫病理特征。然而，目前尚无统一且被广泛接受的标准来定义Eos CRSwNP。本综述的目的是比较当前用于分类Eos CRSwNP的方法的优缺点，以便为进一步研究奠定基础。
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