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[PSK作为胃癌辅助免疫化疗药物的临床研究]

[Clinical study of PSK as an adjuvant immunochemotherapeutic agent against gastric cancer].

作者信息

Mitomi T

出版信息

Gan To Kagaku Ryoho. 1986 Aug;13(8):2532-7.

PMID:3090939
Abstract

The effects of PSK in combination with Mitomycin C, Adriamycin and Tegafur were studied in 168 patients who underwent gastrectomy for gastric cancer. The study group receiving PSK showed improved survival and there was a significant difference in the estimated survival. An improved survival rate was also shown at stages III and IV, in the group given an FAM regimen and in the group with well differentiated adenocarcinoma.

摘要

对168例因胃癌接受胃切除术的患者研究了PSK与丝裂霉素C、阿霉素和替加氟联合使用的效果。接受PSK的研究组生存率提高，估计生存率有显著差异。在III期和IV期、接受FAM方案的组以及高分化腺癌组中也显示出生存率提高。

相似文献

1
[Clinical study of PSK as an adjuvant immunochemotherapeutic agent against gastric cancer].[PSK作为胃癌辅助免疫化疗药物的临床研究]
Gan To Kagaku Ryoho. 1986 Aug;13(8):2532-7.
2
Postoperative adjuvant immunochemotherapy with mitomycin C, tegafur, PSK and/or OK-432 for gastric cancer, with special reference to the change in stimulation index after gastrectomy.胃癌术后使用丝裂霉素C、替加氟、PSK和/或OK-432进行辅助免疫化疗，特别提及胃切除术后刺激指数的变化。
Jpn J Surg. 1990 Mar;20(2):127-36. doi: 10.1007/BF02470759.
3
[Postoperative adjuvant immunochemotherapy with bestatin for stomach cancer. Randomized controlled trial: first report].[胃癌术后使用贝司他汀的辅助免疫化疗。随机对照试验：首次报告]
Gan To Kagaku Ryoho. 1985 Jul;12(7):1458-64.
4
[Multi-institutional cooperative study of adjuvant immunochemotherapy in gastric cancer--five-year survival rate].[胃癌辅助免疫化疗的多机构合作研究——五年生存率]
Gan To Kagaku Ryoho. 1989 Apr;16(4 Pt 1):799-806.
5
[Comparison of immunochemotherapy and chemotherapy of stage IV gastric carcinoma].[IV期胃癌免疫化疗与化疗的比较]
Gan No Rinsho. 1985 Nov;31(14):1805-9.
6
Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer.免疫化疗作为胃癌根治性切除术后辅助治疗的疗效。胃癌PSK免疫化疗研究组。
Lancet. 1994 May 7;343(8906):1122-6. doi: 10.1016/s0140-6736(94)90233-x.
7
[Randomized controlled trial of postoperative adjuvant chemotherapy with bestatin for gastric cancer].[胃癌术后用抑氨肽酶B进行辅助化疗的随机对照试验]
Gan To Kagaku Ryoho. 1985 Jan;12(1):125-33.
8
[A multi-institutional study on postoperative adjuvant immunochemotherapy of gastric cancer].[一项关于胃癌术后辅助免疫化疗的多机构研究]
Gan To Kagaku Ryoho. 1985 Sep;12(9):1850-63.
9
[Effective postoperative chemotherapy of gastric cancer associated with disseminated carcinomatosis of the bone marrow].[胃癌合并骨髓播散性癌病的有效术后化疗]
Gan No Rinsho. 1985 Sep;31(11):1456-62.
10
Adjuvant mitomycin and fluorouracil followed by oral uracil plus tegafur in serosa-negative gastric cancer: a randomised trial. Gastric Cancer Surgical Study Group.丝裂霉素和氟尿嘧啶辅助治疗后口服尿嘧啶加替加氟用于浆膜阴性胃癌：一项随机试验。胃癌外科研究组
Lancet. 1999 Jul 24;354(9175):273-7. doi: 10.1016/s0140-6736(99)01048-x.

引用本文的文献

1
Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer.多糖K辅助免疫化疗对胃癌根治性切除患者的疗效
Cancer Immunol Immunother. 2007 Jun;56(6):905-11. doi: 10.1007/s00262-006-0248-1. Epub 2006 Nov 15.
2
Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer.结直肠癌根治性手术后口服多糖K（PSK）可显著延长无病生存期。
Cancer Immunol Immunother. 1990;31(5):261-8. doi: 10.1007/BF01740932.
3
Glycosidically bound sialic acid levels as a predictive marker of postoperative adjuvant therapy in gastric cancer.
糖苷结合唾液酸水平作为胃癌术后辅助治疗的预测标志物。
Cancer Immunol Immunother. 1992;35(3):175-80. doi: 10.1007/BF01756184.