Higashino Y, Nakamura T, Kato M, Asano E, Akimoto R, Uchida H, Mukawa A, Nagakawa T
Gan No Rinsho. 1985 Sep;31(11):1456-62.
A 35-year-old woman tuffering from gastric cancer associated with disseminated carcinomatosis of the bone marrow is reported. Total gastrectomy combined with splenectomy and distal pancreatectomy was performed. The patient was treated with mitomycin C, FT-207, OK-432, and PSK. But serum ALP (alkaline phosphatase) and CEA (carcinoembryonic antigen) values showed gradual elevations followed by deterioration of the patient's general condition. Consequently, chemotherapy program consisting of 5-fluorouracil, Adriamycin (intra-arterially), and cisplatin (intravenously) was initiated. Serum CEA and ALP values were considerably improved, and patient was restored to a better condition. She survived 17 months and died of disseminated intravascular coagulation.
报告了一名35岁患有胃癌并伴有骨髓播散性癌病的女性。实施了全胃切除术联合脾切除术和远端胰腺切除术。患者接受了丝裂霉素C、替加氟（FT - 207）、溶链菌制剂（OK - 432）和云芝多糖K（PSK）治疗。但血清碱性磷酸酶（ALP）和癌胚抗原（CEA）值逐渐升高，随后患者的一般状况恶化。因此，启动了由5 - 氟尿嘧啶、阿霉素（动脉内给药）和顺铂（静脉内给药）组成的化疗方案。血清CEA和ALP值显著改善，患者恢复到较好状态。她存活了17个月，死于弥散性血管内凝血。
