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毛棉杜鹃花枝叶中的新糖苷。

New glycosides from the twigs and leaves of Rhododendron latoucheae.

作者信息

Wang Ya-Nan, Liu Fei, Li Yong, Ma Shuang-Gang, Qu Jing, Liu Yun-Bao, Niu Chang-Shan, Tang Zhong-Hai, Li Yu-Huan, Wang Ru-Bing, Yu Shi-Shan

机构信息

a State Key Laboratory of Bioactive Substance and Function of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.

b NHC Key Laboratory of Biotechnology of Antibiotics , Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.

出版信息

J Asian Nat Prod Res. 2019 Apr;21(4):299-307. doi: 10.1080/10286020.2019.1585823. Epub 2019 Mar 26.

Abstract

Six new glycosides (1-6), together with three known ones, were isolated from the twigs and leaves of Rhododendron latoucheae. Their structures were elucidated based on the spectroscopic data, including infrared spectrometry, mass spectrometry, and nuclear magnetic resonance experiments, along with Mosher's method. In addition, all compounds were tested their antiviral (herpes simplex virus-1 and influenza A/95-359) activities.

摘要

从拉氏杜鹃的嫩枝和叶子中分离出六种新的糖苷(1-6)以及三种已知的糖苷。基于光谱数据,包括红外光谱、质谱和核磁共振实验,并结合莫舍尔法阐明了它们的结构。此外,对所有化合物进行了抗(单纯疱疹病毒-1和甲型流感病毒/95-359)病毒活性测试。

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