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原位减压与移位治疗特发性肘管综合征的尺神经:一项更新的荟萃分析。

Ulnar Nerve In Situ Decompression versus Transposition for Idiopathic Cubital Tunnel Syndrome: An Updated Meta-Analysis.

作者信息

Said Joseph, Van Nest Duncan, Foltz Carol, Ilyas Asif M

机构信息

Department of Hand and Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, United States.

出版信息

J Hand Microsurg. 2019 Apr;11(1):18-27. doi: 10.1055/s-0038-1670928. Epub 2018 Sep 27.

Abstract

Evidence for the superiority of in situ simple decompression (SD) versus ulnar nerve transposition (UNT) for cubital tunnel syndrome remains controversial. The purpose of this study was to compare the clinical improvement, complication rate, and revision rate of SD versus UNT using the available evidence. We performed a literature search of relevant publications using PubMed, SCOPUS, Cochrane Library, and Springer Link. Inclusion criteria included (1) adult patients >18 years of age, (2) idiopathic cubital tunnel syndrome, (3) primary comparison studies including both SD versus UNT with discrete data for each procedure, (4) average follow-up of at least 2 months, and (5) a full English language manuscript available. Odds ratios of improvement, complications, and revision surgery after SD compared with UNT were calculated. Data were analyzed using both fixed and random effects models, and studies were assessed for publication bias and heterogeneity. A total of 1,511 articles from 1970 to 2017 were identified before inclusion, and exclusion criteria were applied. Ultimately 17 studies met the inclusion criteria and included 2,154 procedures. Of these, 1,040 were SD, and 1,114 were UNT procedures. Study heterogeneity was low. Odds ratios of clinical improvement and revision surgery with SD versus UNT were not significantly different. The odds ratio of complications with SD versus UNT was 0.449 (95% confidence interval [CI] of 0.290-0.695) and 0.469 (95% CI of 0.297-0.738) for fixed and random effect models, respectively. The difference in complications between SD versus UNT was significant ( < 0.001). There is no statistically significant difference in clinical outcomes or rate of revision surgery between SD versus UNT. However, there were significantly more complications with UNT. The current body of evidence regarding cubital tunnel syndrome lacks prospective, randomized, controlled trials, uniform reporting of indications, and standardized outcome scoring.

摘要

对于原位单纯减压术(SD)与尺神经转位术(UNT)治疗肘管综合征的优越性,现有证据仍存在争议。本研究的目的是利用现有证据比较SD与UNT的临床改善情况、并发症发生率及翻修率。我们使用PubMed、SCOPUS、Cochrane图书馆和Springer Link对相关出版物进行了文献检索。纳入标准包括:(1)年龄大于18岁的成年患者;(2)特发性肘管综合征;(3)主要比较研究,包括SD与UNT,且每种手术有离散数据;(4)平均随访至少2个月;(5)有完整的英文手稿。计算了SD与UNT相比改善、并发症及翻修手术的优势比。使用固定效应模型和随机效应模型对数据进行分析,并评估研究的发表偏倚和异质性。纳入前共识别出1970年至2017年的1511篇文章,并应用了排除标准。最终17项研究符合纳入标准,包括2154例手术。其中,1040例为SD手术,1114例为UNT手术。研究异质性较低。SD与UNT相比临床改善和翻修手术的优势比无显著差异。SD与UNT相比并发症的优势比,固定效应模型为0.449(95%置信区间[CI]为0.290 - 0.695),随机效应模型为0.469(95%CI为0.297 - 0.738)。SD与UNT之间并发症的差异具有统计学意义(<0.001)。SD与UNT在临床结局或翻修手术率方面无统计学显著差异。然而,UNT的并发症明显更多。目前关于肘管综合征的证据缺乏前瞻性、随机、对照试验,适应证的统一报告以及标准化的结局评分。

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