McGonigle Ian, Schuster Stephan C
School of Social Sciences,Nanyang Technological University,Singapore.
School of Biological Sciences,Nanyang Technological University,Singapore.
Genet Res (Camb). 2019 Mar 26;101:e5. doi: 10.1017/S001667231800006X.
GenomeAsia100K is a human genome project based at Nanyang Technological University in Singapore that aims to sequence one hundred thousand Asian genomes in an effort that addresses an ethnic bias towards Western populations in previous genomic research. GenomeAsia100K consists of a team of bioinformaticians, statisticians and population geneticists, and was initiated by the Nanyang Technological University in collaboration with industrial partners MedGenome (an Indian R&D company specializing in genomic data) and the California Biotech company Genentech. The GenomeAsia100K project is amongst the most ambitious precision medicine projects to date but it is not clear how the project will challenge or reshape understandings of ethnic and racial differences in Asian populations. Ian McGonigle, a scientist and cultural anthropologist, sat down with geneticist Stephan C. Schuster, the scientific chairman of GenomeAsia100K, to discuss the project and the implications of genomics for social identity in the 21st century.
“亚洲基因组计划100K”是一个总部位于新加坡南洋理工大学的人类基因组项目，旨在对10万个亚洲人的基因组进行测序，以解决以往基因组研究中对西方人群的种族偏见问题。“亚洲基因组计划100K”由一群生物信息学家、统计学家和群体遗传学家组成，由南洋理工大学与行业合作伙伴MedGenome（一家专注于基因组数据的印度研发公司）和加州生物技术公司基因泰克合作发起。“亚洲基因组计划100K”项目是迄今为止最雄心勃勃的精准医学项目之一，但尚不清楚该项目将如何挑战或重塑对亚洲人群族裔和种族差异的理解。科学家兼文化人类学家伊恩·麦戈尼格尔与“亚洲基因组计划100K”的科学主席、遗传学家斯蒂芬·C·舒斯特坐下来，讨论了该项目以及基因组学对21世纪社会身份的影响。
