Occupational Health and Prevention Department, Fundación Jiménez Díaz University Hospital, Madrid, Spain.
Radiological Protection Service, Fundación Jiménez Díaz University Hospital, Madrid, Spain.
Health Phys. 2019 Oct;117(4):403-407. doi: 10.1097/HP.0000000000001071.
To analyze possible alterations of thyroid function related to dosimetric values in health care workers exposed to ionizing radiation.
Forty-six health care workers exposed to ionizing radiation at a tertiary hospital previously exposed to ionizing radiation were included in the study. Age, sex, history of thyroid diseases, thyroid hormones, work post, service, dosimetric values of previous year, and 5 y period were considered. Alterations of thyroid function and other variables were analyzed by exact logistic regression univariate model.
7.1% workers showed an increased serum thyroid-stimulating hormone without free T3 or free T4 alteration. A significant relationship between workers with increased thyroid-stimulating hormone and dosimetric values of previous year (odds ratio 6.35, 95% confidence interval 1.20-98.1, p = 0.021) and previous 5 y period of radiation exposure (odds ratio 1.72, 95% confidence interval 1.12-3.34, p = 0.007) was obtained.
An increased risk of subclinical hypothyroidism related to radiation doses was observed in this pilot study on a group of health care workers exposed to ionizing radiation.
分析与接触电离辐射的医护人员剂量学值相关的甲状腺功能变化。
本研究纳入了 46 名曾在一家三级医院接触过电离辐射的医护人员。考虑了年龄、性别、甲状腺疾病史、甲状腺激素、工作岗位、工作年限、前一年的剂量学值以及 5 年期间。通过单变量精确逻辑回归模型分析了甲状腺功能改变和其他变量。
7.1%的工人表现出血清促甲状腺激素升高，而游离 T3 或游离 T4 没有改变。在接受过增加的甲状腺刺激激素的工人和前一年（优势比 6.35，95%置信区间 1.20-98.1，p = 0.021）和前 5 年的辐射暴露（优势比 1.72，95%置信区间 1.12-3.34，p = 0.007）的剂量学值之间存在显著关系。
在这项对接触电离辐射的医护人员进行的初步研究中，观察到亚临床甲状腺功能减退症的风险与辐射剂量有关。
