Department of Biology, University of Maryland, College Park, MD 20742, USA.
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
Dev Cell. 2019 Mar 25;48(6):744-746. doi: 10.1016/j.devcel.2019.03.005.
Reporting in Developmental Cell, Cenik et al. (2019) show that the maternal ribosome supply is sufficient for C. elegans embryonic development, arguing against tissue-specific specialized ribosomes in this context. Examination of ribosomal requirement with the genetic tool kit presented in Artiles et al. (2019) suggests a checkpoint that prevents uncoordinated growth.
在《发育细胞》杂志上，Cenik 等人（2019 年）报告称，母体核糖体的供应足以满足秀丽隐杆线虫胚胎的发育，这一结果否定了在这种情况下组织特异性的专门核糖体的存在。利用 Artiles 等人（2019 年）提出的遗传工具包检查核糖体的需求，提示存在一个防止不协调生长的检查点。
