Heim M E
Infusionsther Klin Ernahr. 1986 Jun;13(3):115-21.
Adjuvant parenteral nutrition of tumor patients receiving cytotoxic chemotherapy offers many potential advantages. There are some randomized studies with few cases looking at the effect of parenteral nutrition on tumor response and toxicity. In an own prospective randomized study on parenteral nutrition of colorectal cancer patients an increase of tumor response, prolongation of survival, or reduction of toxicity could not be achieved. Published controlled studies are discussed in a literature review. Parenteral nutrition of tumor patients receiving chemotherapy is not principally advantageous and should be restricted to special clinical situations.
接受细胞毒性化疗的肿瘤患者辅助肠外营养有许多潜在益处。有一些病例数较少的随机研究观察了肠外营养对肿瘤反应和毒性的影响。在一项关于结直肠癌患者肠外营养的自身前瞻性随机研究中,未能实现肿瘤反应增加、生存期延长或毒性降低。文献综述中讨论了已发表的对照研究。接受化疗的肿瘤患者进行肠外营养并非主要有益,应限于特殊临床情况。