Müller J M, Keller H W, Brenner U, Walter M
Leber Magen Darm. 1984 Mar;14(2):68-77.
Between 30 and 60% of all carcinoma patients are already in deficient nutritional status at the time when diagnosis of the disease is established. The pathogenesis of this deficit is multifactorial. Increased caloric needs as caused by the malignoma as well as loss of adaptability of the tumor patient to reduced nutritional intake may be decisive factors. Effective parenteral nutrition is possible before, but only rarely during oncological therapy. Prospective studies have shown up to now only in tumor surgery but not in patients treated only with chemotherapy or with radiation therapy of malignoma that adjuvant parenteral nutrition may improve the results of treatment as determined by prolongation of life. The role of parenteral nutrition as an adjuvant therapeutic step in oncology has to be defined more clearly in the future, as is the case with most other adjuvant therapeutic measures.
在所有癌症患者中，30%至60%在确诊疾病时就已处于营养缺乏状态。这种营养缺乏的发病机制是多因素的。恶性肿瘤导致的热量需求增加以及肿瘤患者对营养摄入减少的适应能力丧失可能是决定性因素。在肿瘤治疗前可以进行有效的肠外营养，但在肿瘤治疗期间则很少进行。迄今为止，前瞻性研究仅在肿瘤手术患者中发现，而在仅接受化疗或恶性肿瘤放疗的患者中未发现，辅助性肠外营养可能通过延长生存期来改善治疗效果。与大多数其他辅助治疗措施一样，肠外营养作为肿瘤学辅助治疗步骤的作用在未来必须更明确地界定。
