Department of Anesthesia and Intensive Care, Hôpitaux Universitaires de Strasbourg, Nouvel Hôpital Civil, Strasbourg, France.
Department of Immunology, Allergology and Rheumatology, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Br J Anaesth. 2019 Jul;123(1):e16-e28. doi: 10.1016/j.bja.2019.01.027. Epub 2019 Mar 4.
Suspected perioperative hypersensitivity reactions are rare but contribute significantly to the morbidity and mortality of surgical procedures. Recent publications have highlighted the differences between countries concerning the respective risk of different drugs, and changes in patterns of causal agents and the emergence of new allergens. This review summarises recent information on the epidemiology of perioperative hypersensitivity reactions, with specific consideration of differences between geographic areas for the most frequently involved offending agents.
疑似围手术期过敏反应虽罕见，但对手术的发病率和死亡率有重大影响。近期出版物强调了不同国家之间关于不同药物的风险差异，以及致病因子模式的变化和新过敏原的出现。本文综述了围手术期过敏反应的最新流行病学信息，并特别考虑了最常涉及的致敏药物在不同地理区域之间的差异。
