Huang Dao-Yu, Shen Ya-Jun, Wang Fei, Li Fang, Fang Zhao, Liu Jun
Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu, China;
Zhongguo Gu Shang. 2019 Mar 25;32(3):244-247. doi: 10.3969/j.issn.1003-0034.2019.03.010.
To investigate the correlation between degenerative lumbar scoliosis and osteoporosis in adults.
From March 2012 to June 2016, the clinical data of 53 patients with degenerative lumbar scoliosis were retrospectively analyzed for a correlation study between degenerative lumbar scoliosis and osteoporosis. Fifty-three patients with degenerative lumbar scoliosis were selected as observation group and another 53 inpatients without lumbar scoliosis as control group. There were 11 males and 42 females with an average age of 69 years (range 63 to 76 years) old in observation group. And in control group, there were 16 males and 37 females with an average age of 68.5 years (range 59 to 74 years) old, including lumbar disc herniation in 33 cases, lumbar spinal stenosis in 13 cases, spondylolisthesis in 7 cases. The 53 patients with degenerative lumbar scoliosis were confirmed by X-ray and MRI, their Cobb angle of lumbar scoliosis was measured. Dual energy X-ray absorptiometry was used to measure the bone mineral density, the T values of L₂-L₄ segments, femoral neck, Ward triangle and femoral trochanter were recorded. Linear regression analysis was used to analyze the correlation between osteoporosis and degenerative lumbar scoliosis.
There were significant differences in the bone mineral density T values between two groups (<0.05). Bone mineral density T value in patients with lumbar scoliosis were significantly higher than that in the patients with no lumbar scoliosis (<0.05), (-2.56±0.65 vs -1.39±0.77). The T values of L₂-L₄ segments, femoral neck, Ward triangle and femoral trochanter had no remarkable correlation with Cobb's angles.
Osteoporosis is a risk factor for degenerative scoliosis, but the severity of osteoporosis and degree of scoliosis has no obvious correlation.
探讨成人退变性腰椎侧凸与骨质疏松症之间的相关性。
回顾性分析2012年3月至2016年6月期间53例退变性腰椎侧凸患者的临床资料,以研究退变性腰椎侧凸与骨质疏松症之间的相关性。选取53例退变性腰椎侧凸患者作为观察组,另选53例无腰椎侧凸的住院患者作为对照组。观察组中男性11例,女性42例,平均年龄69岁(范围63至76岁)。对照组中男性16例,女性37例,平均年龄68.5岁(范围59至74岁),其中腰椎间盘突出症33例,腰椎管狭窄症13例,椎体滑脱7例。53例退变性腰椎侧凸患者经X线和MRI确诊,测量其腰椎侧凸的Cobb角。采用双能X线吸收法测量骨密度,记录L₂-L₄节段、股骨颈、Ward三角和股骨大转子的T值。采用线性回归分析骨质疏松症与退变性腰椎侧凸之间的相关性。
两组骨密度T值差异有统计学意义(<0.05)。腰椎侧凸患者的骨密度T值显著高于无腰椎侧凸患者(<0.05),(-2.56±0.65 vs -1.39±0.77)。L₂-L₄节段、股骨颈、Ward三角和股骨大转子的T值与Cobb角无显著相关性。
骨质疏松症是退变性脊柱侧凸的危险因素,但骨质疏松症的严重程度与脊柱侧凸程度无明显相关性。