细胞松弛素B改变新城疫病毒感染细胞中的细胞骨架组织。
Cytochalasin B changes the cytoskeletal organization in Newcastle disease virus-infected cells.
作者信息
Chen W F, Soong M M, Liang S C, Wang D M
出版信息
Proc Natl Sci Counc Repub China B. 1986 Apr;10(2):137-44.
The microfilament structures of Newcastle disease virus (NDV)-infected BHK-21 cells were studied in the presence (5 micrograms/ml) or absence of cytochalasin B (CB) by means of phase contrast, indirect immunofluorescence and thin-section immunoelectron microscopy. The results indicated that CB treatment not only impaired virus infections titers and antiactin fluorescence strength but also disrupted cytoplasmic membrane and untagged ferritin-conjugated antibody on the surface of NDV specific antigens.
利用相差显微镜、间接免疫荧光和超薄切片免疫电子显微镜技术，在存在（5微克/毫升）或不存在细胞松弛素B（CB）的情况下，研究了新城疫病毒（NDV）感染的BHK - 21细胞的微丝结构。结果表明，CB处理不仅损害病毒感染滴度和抗肌动蛋白荧光强度，还破坏细胞质膜以及NDV特异性抗原表面未标记的铁蛋白偶联抗体。
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