Department of Epidemiology and Medical Statistics, Xiangya School of Public Health, Central South University, Xiangya Road 110, Changsha 410078, China.
Int J Environ Res Public Health. 2019 Mar 28;16(7):1110. doi: 10.3390/ijerph16071110.
The association of maternal parity, pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) with childhood weight status has been well studied; however, little is known about these factors with respect to the rate of weight changes in early childhood.
This study was based on a prospective longitudinal study. The follow-up surveys were conducted at the ages of 1, 3, 6, 8, 12, and 18 months. Child weight was investigated twice at each wave. Data on maternal parity, pre-pregnancy weight and height were collected at baseline. The latent growth curve model was used to examine the effects of interested predictors on the trajectory of weight in early childhood.
Finally, 893 eligible mother-child pairs were drawn from the cohort. In adjusted models, multiparas were associated with higher birth weight (β = 0.103) and slower weight change rate of children (β = -0.028). Pre-conception BMI (β = 0.034) and GWG (β = 0.014) played important roles in the initial status of child weight but did not have effects on the rate of weight changes of the child.
Multiparous pregnancy is associated with both higher mean birth weight and slower weight-growth velocity in early childhood, while pregravid maternal BMI and GWG are only related to the birth weight.
母体生育次数、孕前体重指数（BMI）和孕期体重增加（GWG）与儿童体重状况的关联已得到充分研究；然而，对于这些因素与儿童早期体重变化率的关系，知之甚少。
本研究基于一项前瞻性纵向研究。随访调查在 1、3、6、8、12 和 18 个月时进行。每个阶段均对儿童体重进行两次调查。在基线时收集了母亲生育次数、孕前体重和身高的数据。使用潜在增长曲线模型来检验感兴趣的预测因素对儿童早期体重轨迹的影响。
最终，从队列中抽取了 893 对符合条件的母婴对。在调整后的模型中，多产妇与更高的出生体重（β=0.103）和儿童体重变化率更慢（β=-0.028）有关。孕前 BMI（β=0.034）和 GWG（β=0.014）在儿童体重的初始状态中起着重要作用，但对儿童体重变化率没有影响。
多胎妊娠与儿童早期的平均出生体重较高和体重增长速度较慢有关，而孕前母体 BMI 和 GWG 仅与出生体重有关。
