文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

骨瓣回植是否会导致脑膜瘤术后复发?一项观察性前瞻性研究。

Does Putting Back Hyperostotic Bone Flap in Meningioma Surgery Cause Tumor Recurrence? An Observational Prospective Study.

机构信息

Department of Neurosurgery, Sarawak General Hospital, Ministry of Health, Jalan Hospital, Kuching, Malaysia.

Department of Neurosurgery, Sarawak General Hospital, Ministry of Health, Jalan Hospital, Kuching, Malaysia.

出版信息

World Neurosurg. 2019 Jul;127:e497-e502. doi: 10.1016/j.wneu.2019.03.183. Epub 2019 Mar 26.


DOI:10.1016/j.wneu.2019.03.183
PMID:30926555
Abstract

BACKGROUND: Replacing the skull defect with synthetic materials for hyperostotic bone secondary to meningioma is recommended owing to the possibility of tumor invasion. In our institution, neurosurgeons have been putting back the refashioned hyperostotic bone flap after meningioma excision because of budget constraints. The aim of this study was to review the long-term meningioma recurrence rate in these patients. METHODS: This was a nonrandomized, prospective observational study conducted from September 2011 to January 2015 on patients with intracranial convexity and parasagittal meningiomas. Preoperative computed tomography brain scans were obtained in all patients to confirm bony hyperostosis. Intraoperatively, part of the hyperostotic bone was sent for histopathologic examination. The rest of the bone flap was refashioned by drilling off the hyperostotic part. The bone flap was put back over the craniotomy site after soaking in distilled water. All patients were followed up for tumor recurrence. RESULTS: The study included 34 patients with convexity or parasagittal meningioma World Health Organization grade I-II who underwent Simpson grade Ia and IIa excision. Median follow-up was 63.5 months (mean 64.9 ± 9.4 months). The hyperostotic bone flap showed presence of tumor in 35% of patients. There were 2 patients with parasagittal meningiomas after Simpson grade IIa resections who developed tumor recurrences. CONCLUSIONS: Our study found that meningioma recurrence was unlikely when autologous cranioplasty was done with refashioned hyperostotic bone. This could be done in the same setting with meningioma excision. There was no recurrence in convexity meningiomas at mean 5-year follow-up.

摘要

背景:由于存在肿瘤侵袭的可能性,建议用合成材料替代因脑膜瘤导致的骨质过度增生的颅骨缺损。由于预算限制,我院神经外科医生在切除脑膜瘤后会将整形后的骨质瓣放回原处。本研究旨在回顾这些患者的脑膜瘤长期复发率。

方法:这是一项从 2011 年 9 月至 2015 年 1 月进行的非随机、前瞻性观察研究,纳入对象为颅内凸面和矢状旁脑膜瘤患者。所有患者均行术前颅脑 CT 扫描以确认骨质过度增生。术中部分骨质过度增生的部分送组织病理学检查,其余骨质用钻孔去除过度增生的部分进行整形。将骨质瓣浸泡在蒸馏水中后放回颅骨切开部位。所有患者均随访肿瘤复发情况。

结果:研究纳入了 34 例接受 World Health Organization 分级 I-II 级 Simpson 分级 Ia 和 IIa 切除的凸面或矢状旁脑膜瘤患者。中位随访时间为 63.5 个月(平均 64.9 ± 9.4 个月)。骨质瓣显示有肿瘤存在于 35%的患者中。2 例接受 Simpson 分级 IIa 切除的矢状旁脑膜瘤患者出现肿瘤复发。

结论:我们的研究发现,用整形后的骨质进行自体颅骨修复时,脑膜瘤复发的可能性较小。可以在切除脑膜瘤的同一情况下进行。在平均 5 年的随访中,凸面脑膜瘤无复发。

相似文献

[1]
Does Putting Back Hyperostotic Bone Flap in Meningioma Surgery Cause Tumor Recurrence? An Observational Prospective Study.

World Neurosurg. 2019-3-26

[2]
Does bony hyperostosis in intracranial meningioma signify tumor invasion? A radio-pathologic study.

Neurol India. 2012

[3]
WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant?

Clin Neurol Neurosurg. 2016-2

[4]
Management of bone-invasive, hyperostotic sphenoid wing meningiomas.

J Neurosurg. 2007-11

[5]
Domestic software, medical devices and materials in surgery for hyperostotic craniofacial meningiomas.

Zh Vopr Neirokhir Im N N Burdenko. 2023

[6]
Relevance of Simpson grading system and recurrence-free survival after surgery for World Health Organization Grade I meningioma.

J Neurosurg. 2016-4-8

[7]
[Relevance of Simpson's grading system for resections in WHO grade I meningiomas].

Neurocirugia (Astur). 2017

[8]
Convexity meningiomas: study of recurrence factors with special emphasis on the cleavage plane in a series of 100 consecutive patients.

J Neurosurg. 2011-6-10

[9]
A giant hyperostosing meningioma in a child.

Neurochirurgia (Stuttg). 1992-9

[10]
Extent of Hyperostotic Bone Resection in Convexity Meningioma to Achieve Pathologically Free Margins.

J Korean Neurosurg Soc. 2020-11

引用本文的文献

[1]
Cranioplasty After Removal of a Meningioma With Skull Invasion: A Technical Case Report.

Cureus. 2025-5-21

[2]
Radiotherapy and radiosurgery for meningiomas.

Neurooncol Adv. 2023-6-3

[3]
Cranial meningioma with bone involvement: surgical strategies and clinical considerations.

Acta Neurochir (Wien). 2023-5

[4]
Multiple Meningioma Resection by Bilateral Extended Rostrotentorial Craniotomy with a 3D-Print Guide in a Cat.

Vet Sci. 2022-9-20

[5]
Evaluation of Magnetic Resonance Imaging for Microsurgical Efficacy and Relapse of Rolandic Meningioma.

Comput Intell Neurosci. 2022

[6]
Extent of Hyperostotic Bone Resection in Convexity Meningioma to Achieve Pathologically Free Margins.

J Korean Neurosurg Soc. 2020-11

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索