Department of Neurosurgery, Changde First People's Hospital, Changde 415000, Hunan, China.
Comput Intell Neurosci. 2022 Jun 6;2022:1026494. doi: 10.1155/2022/1026494. eCollection 2022.
In this study, magnetic resonance imaging (MRI) was used to evaluate the relapse features of patients with Rolandic meningioma after the microsurgery. 53 patients with Rolandic meningioma were selected as the research objects, and they were divided into the relapse group ( = 16) and nonrelapse group ( = 37) according to whether patients had a relapse during the follow-up period. Differences in quality of life, H-MRS index, vascular density, and cell proliferation between the two groups were assessed as well as imaging differences between the two groups were analyzed using MRI. The results showed that the patients' quality-of-life scores in the two groups increased notably after the surgical treatment ( < 0.05). Compared with the nonrelapse group, the proportion of irregular boundary and uneven enhancement of focal tissue in the relapse group was signally increased ( < 0.05). Compared with the nonrelapse group, cell proliferation index, vascular density and imaging index, mean tumor diameter, mean transit time (MTT), time to peak (TTP), fractional anisotropy (FA), choline (Cho)/N-acetylaspartic acid (NAA), Cho/creatine (Cr), lactic acid (Lac)/Cr, and the maximum value of relative cerebral blood volume (rCBVmax) in the relapse group were obviously increased ( < 0.05). However, the apparent dispersion coefficient, NAA/Cr, and Lac/NAA values decreased greatly ( < 0.05). To sum up, the microsurgical treatment helped improve the quality of life of patients with Rolandic meningioma, and MR imaging could be used to determine the relapse of Rolandic meningioma after microsurgical treatment.
在这项研究中，磁共振成像（MRI）用于评估显微手术后 Rolandic 脑膜瘤患者的复发特征。选择 53 例 Rolandic 脑膜瘤患者作为研究对象，根据患者在随访期间是否复发，分为复发组（n=16）和非复发组（n=37）。评估两组患者的生活质量、H-MRS 指数、血管密度和细胞增殖差异，分析两组患者的 MRI 影像学差异。结果显示，两组患者手术后生活质量评分明显提高（P<0.05）。与非复发组相比，复发组局灶性组织边界不规则和不均匀增强的比例明显增加（P<0.05）。与非复发组相比，复发组细胞增殖指数、血管密度和影像学指标，包括平均肿瘤直径、平均通过时间（MTT）、达峰时间（TTP）、各向异性分数（FA）、胆碱（Cho）/N-乙酰天门冬氨酸（NAA）、Cho/肌酸（Cr）、乳酸（Lac）/Cr 和相对脑血容量最大值（rCBVmax）明显升高（P<0.05）。然而，表观弥散系数、NAA/Cr 和 Lac/NAA 值明显降低（P<0.05）。综上所述，显微手术治疗有助于改善 Rolandic 脑膜瘤患者的生活质量，MRI 可用于确定显微手术后 Rolandic 脑膜瘤的复发。
