年轻患者中罕见的多形性低级别神经上皮肿瘤病例报告，并与少突胶质细胞瘤进行比较。
Case Report of Rarely Described Polymorphous Low-Grade Neuroepithelial Tumor of the Young and Comparison with Oligodendroglioma.
机构信息
Seton Medical Center Williamson, Round Rock, Texas, USA.
Seton Medical Center Williamson, Round Rock, Texas, USA.
出版信息
World Neurosurg. 2019 Jul;127:47-51. doi: 10.1016/j.wneu.2019.03.181. Epub 2019 Mar 26.
BACKGROUND
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a central nervous system tumor that shares many qualities with oligodendroglioma but is rarely and only very recently described as a distinct entity in the literature.
CASE DESCRIPTION
A previously healthy, 19-year-old man presented with new onset of seizures. Imaging showed an intracranial mass, which was treated with surgical removal. Preoperative and postoperative magnetic resonance imaging, histopathologic examination, genetic testing, and immunohistochemical staining all supported a diagnosis of PLNTY.
CONCLUSIONS
Diagnostic investigation of PLNTY shows many similarities with oligodendroglioma, and thus these entities can be mistaken for one another. Certain studies are needed to distinguish PLNTY and other dysembryoplastic neuroepithelial tumors, such as oligodendroglioma.
背景
年轻多形性低级别神经上皮肿瘤（PLNTY）是一种中枢神经系统肿瘤，与少突胶质细胞瘤有许多共同特征，但在文献中很少且直到最近才被描述为一个独特的实体。
病例描述
一位既往健康的 19 岁男性出现新发癫痫。影像学检查显示颅内有一个肿块，通过手术切除进行了治疗。术前和术后磁共振成像、组织病理学检查、基因检测和免疫组织化学染色均支持 PLNTY 的诊断。
结论
PLNTY 的诊断研究与少突胶质细胞瘤有许多相似之处，因此这些实体可能会被误诊。需要进行某些研究来区分 PLNTY 和其他发育不良性神经上皮肿瘤，如少突胶质细胞瘤。
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