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[46例新生儿大血管单纯转位解剖矫治的结果]

[Results of anatomical correction of simple transposition of the great vessels in 46 newborn infants].

作者信息

Sidi D, Planché C, Kachaner J, Bruniaux J, Villain E, Piéchaud J F, Lacour-Gayet F

出版信息

Arch Mal Coeur Vaiss. 1986 May;79(5):693-9.

PMID:3092769
Abstract

Between the 4th April 1984 and 6th December 1984, a strategy of anatomical correction of transposition of the great arteries was undertaken in the newborn if three criteria were respected: parental consent, patient's age of less than 15 days and satisfactory left ventricular geometry. We report our results in 47 consecutive cases operated by the same surgeon at an average age of 8.2 +/- 5.3 days. Atrioseptostomy was performed in all cases before surgery, with a ratio of left to right systolic ventricular pressures greater than 0.66 (m = 0.8) and an infusion of prostaglandin E1 was maintained until surgery in 40 cases. The geometry of the left ventricle assessed by echocardiography was considered to be normal in 23 cases, satisfactory in 22 cases and unfavourable in 2 cases. Except for one case with the great vessels situated in the frontal plane in which an atrial correction was decided upon during surgery, all the patients underwent detransposition under cardiopulmonary bypass without cardiac arrest, irrespective of the coronary anatomy. The pulmonary tract was reconstructed by direct anastomosis with a piece of tanned (first 25 cases) or autologous (following 21 cases) pericardium. There were 18 immediate deaths (17%) but only 4 out of 37 after September 1984 (11%); the causes of failure were: 5 technical errors, 1 irreducible postoperative pulmonary hypertension and 2 probable left ventricular failures. The 38 survivors were followed up for an average of 6.8 +/- 5.4 months (range 1 to 21 months; 28 cases were followed up for over 3 months).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1984年4月4日至1984年12月6日期间,对于新生儿,如果符合三个标准,即获得父母同意、患者年龄小于15天且左心室形态满意,便采取大动脉转位的解剖矫正策略。我们报告了由同一位外科医生连续手术的47例病例的结果,这些病例的平均年龄为8.2±5.3天。所有病例在手术前均进行了房间隔造口术,左心室与右心室收缩压之比大于0.66(中位数为0.8),40例患者在手术前持续输注前列腺素E1。通过超声心动图评估,23例患者的左心室形态正常,22例满意,2例不佳。除1例大血管位于额面的病例在手术中决定进行心房矫正外,所有患者均在体外循环下进行大动脉调转术,不进行心脏停搏,无论冠状动脉解剖结构如何。肺动脉采用一块鞣制(最初25例)或自体(之后21例)心包直接吻合进行重建。有18例即刻死亡(17%),但1984年9月之后的37例中仅有4例死亡(11%);失败原因包括:5例技术失误、1例术后肺动脉高压无法缓解和2例可能的左心室衰竭。38例幸存者平均随访6.8±5.4个月(范围1至21个月;28例随访超过3个月)。(摘要截断于250字)

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