Cloez J L, Isaaz K, Marchal C, Morizot D, Pernot C
Arch Mal Coeur Vaiss. 1986 May;79(5):719-24.
The aim of this study was to evaluate Doppler echocardiography in the non invasive assessment of pulmonary artery pressures in children with patent ductus arteriosus. Systolic pulmonary artery pressure was measured simultaneously at cardiac catheterisation and by pulsed Doppler in 11 children (mean age 1.8 +/- 2 years) with patent ductus arteriosus alone (6 cases) or associated with a malformation of the heart or great arteries (5 cases). Doppler assessment of systolic pulmonary artery pressure was performed by subtracting the value of the maximal pressure gradient between the aorta and pulmonary artery from the systolic systemic pressure measured simultaneously by sphygmomanometry. The maximal pressure gradient between the aorta and pulmonary artery was calculated using the modified Bernouilli formula and the maximal velocity (v) of the shunt flow (gradient = 4 v2). Ductal flow was recorded from the suprasternal approach by direct interrogation of the patent ductus visualised by 2D echocardiography. The systolic pulmonary arterial pressure measured by catheterisation ranged from 21 to 82 mmHg (mean 58 +/- 21 mm Hg) and by pulsed Doppler from 20 to 89 mm Hg (mean 56 +/- 24 mm Hg) (correlation r = 0.94). This study illustrates the value of Doppler echocardiography in the assessment of systolic pulmonary artery pressures in children with patent ductus arteriosus.
本研究的目的是评估多普勒超声心动图在无创评估动脉导管未闭患儿肺动脉压力中的应用。对11例（平均年龄1.8±2岁）单纯动脉导管未闭（6例）或合并心脏或大动脉畸形（5例）的患儿，在心脏导管检查时同步测量收缩期肺动脉压力，并采用脉冲多普勒进行测量。通过从同时用血压计测量的收缩期体循环压力中减去主动脉与肺动脉之间的最大压力阶差来进行收缩期肺动脉压力的多普勒评估。使用改良的伯努利公式计算主动脉与肺动脉之间的最大压力阶差以及分流血流的最大速度（v）（压力阶差=4v²）。通过二维超声心动图显示动脉导管，直接从胸骨上窝切面记录导管血流。导管检查测量的收缩期肺动脉压力范围为21至82 mmHg（平均58±21 mmHg），脉冲多普勒测量的范围为20至89 mmHg（平均56±24 mmHg）（相关系数r = 0.94）。本研究说明了多普勒超声心动图在评估动脉导管未闭患儿收缩期肺动脉压力中的价值。
