[Determination of pressure gradient across patent ductus arteriosus with simultaneous continuous wave Doppler and catheterization methods and non-invasive estimation of pulmonary artery pressure].

To evaluate the accuracy of Doppler technique for measuring the pressure gradient (delta P) across patent ductus arteriosus (PDA) with a simplified Bernoulli equation (delta P = 4 V2) and estimating the pulmonary artery pressure (PAP) by subtracting delta P from brachial arterial pressure (BAP) measured with cuff sphygmomanometry, Doppler echocardiography and catheterization (both left and right) were performed simultaneously in 20 patients with PDA. For the values of systolic peak delta P (SPPG), mean delta P (MPG) and end-diastolic delta P (EDPG) determined by both Doppler and catheter, the correlation was excellent (r = 0.99, 0.99, 0.99). Doppler determined SPPG also correlated well with catheter determined peak to peak delta P (P-PPG) (r = 0.97). Comparison between Doppler-derived and catheter measured systolic PAP (SPAP), mean PAP (MPAP) and diastolic PAP (DPAP) also showed high correlation (r = 0.95, 0.98, 0.97). This study demonstrates that Doppler echocardiography is valuable for measurement of delta P across PDA and non-invasive estimation of PAP in patients with PDA.