Danil'chenko S A, Shlopov V G, Serniak P S, Geev Iu V
Arkh Patol. 1986;48(7):31-5.
Clinical and morphological features of urinary bladder transitional carcinoma pathomorphosis after regional endolymphic polychemotherapy were studied to estimate the criteria of treatment efficiency and prognosis. Quantitative assessment of chemosensitive and chemoresistant tumours is given. The degree of cataplasia, growth character, the amount of stroma, blood supply and intensity of mononuclear infiltration predetermine the stage of pathomorphosis, efficiency of bladder cancer treatment. Studies of stromal immunomorphology, features of blood supply, mechanisms of neoplastic angiogenesis provide better understanding of biological nature of tumours, improve prognosis and choice of treatment.
研究了膀胱移行癌区域内淋巴多药化疗后病理形态变化的临床和形态学特征，以评估治疗效果和预后标准。给出了对化疗敏感和耐药肿瘤的定量评估。化生程度、生长特征、间质数量、血液供应和单核浸润强度决定了病理形态变化阶段和膀胱癌治疗效果。对间质免疫形态学、血液供应特征、肿瘤血管生成机制的研究有助于更好地理解肿瘤的生物学特性，改善预后和治疗选择。
