School of Pharmacy, University of Sydney, Sydney, New South Wales, Australia.
Centre for Behavioural Medicine, UCL School of Pharmacy, University College, London, United Kingdom.
Patient Educ Couns. 2019 Jun;102(6):1203-1209. doi: 10.1016/j.pec.2019.01.019. Epub 2019 Jan 24.
Adherence to topical corticosteroids (TCS) for inflammatory skin conditions is sub-optimal. This Australian study aimed to test the hypothesis that patients who are more satisfied with the level of information they receive about TCS, are less concerned about using TCS and more adherent to healthcare professionals' instructions.
Individuals who were prescribed or had used TCS in the past month were invited to complete an online cross-sectional survey. Reliability and validity of multi-item scales were tested using confirmatory factor analysis. Self-reported adherence to TCS was measured with MARS-5. Multivariate regression with mediation analyses was used to explore relationships between variables.
Mediation analyses of 195 survey (64.4%) responses was performed. Overall satisfaction with information about TCS action and usage (SIMS-AU) (mean = 60.7%) was higher than potential concerns (SIMS-PC) (mean = 48.2%). Analysis revealed that the SIMS subscales were highly correlated (α = 0.57, p < 0.05). Higher overall SIMS scores were predictive of stronger beliefs that TCS was beneficial, fewer concerns about TCS and better adherence.
Being more satisfied with TCS information was associated with having more favourable disposition towards TCS and higher adherence.
Healthcare professionals should identity areas of dissatisfaction with medication information and tailor their counselling accordingly.
对于炎症性皮肤疾病,患者外用皮质类固醇(TCS)的依从性并不理想。本项澳大利亚研究旨在验证以下假设,即那些对 TCS 相关信息的满意度更高的患者,对 TCS 的使用顾虑更少,且更能遵循医护人员的指导。
过去一个月内开具或使用过 TCS 的个体受邀参与在线横断面调查。采用验证性因子分析检验多项目量表的信度和效度。采用 MARS-5 量表评估 TCS 的自我报告依从性。采用多元回归和中介分析来探索变量之间的关系。
对 195 份调查(64.4%)回复进行了中介分析。关于 TCS 作用和使用信息的总体满意度(SIMS-AU)(均值=60.7%)高于潜在顾虑(SIMS-PC)(均值=48.2%)。分析显示,SIMS 分量表高度相关(α=0.57,p<0.05)。更高的总体 SIMS 评分预示着患者对 TCS 更有利的信念、更少的 TCS 使用顾虑和更好的依从性。
对 TCS 信息更满意与对 TCS 更有利的倾向和更高的依从性相关。
医护人员应确定对药物信息不满意的领域,并相应地调整他们的咨询。