Santus R, Reyftmann J P
Biochimie. 1986 Jun;68(6):843-8. doi: 10.1016/s0300-9084(86)80099-2.
The chemical mechanisms of the photosensitized peroxidation of unsaturated fatty acids and cholesterol are reviewed and the subsequent reactions of peroxide decomposition products with biological targets such as DNA and amino acids are analyzed. The importance of protein photooxidation and cross-linking in membrane function impairment is discussed.
综述了不饱和脂肪酸和胆固醇光敏过氧化的化学机制,并分析了过氧化物分解产物与DNA和氨基酸等生物靶点的后续反应。讨论了蛋白质光氧化和交联在膜功能损伤中的重要性。