Abdalla Abubaker O, Alluri Deepti, Hassaballa Mohamed, Calvo Lisa, Otaki Fouad
Department of Internal Medicine, University of Nevada, School of Medicine, Reno, NV, USA.
Department of Gastroenterology, Oregon Health and Science University, Portland, OR, USA.
Am J Case Rep. 2019 Mar 31;20:419-422. doi: 10.12659/AJCR.913429.
BACKGROUND Extra-intestinal manifestations of inflammatory bowel disease (IBD) include thromboembolic events that can present as deep vein thrombosis, pulmonary embolism, and cerebral venous sinus thrombosis. Cerebral venous sinus thrombosis is a rare complication of IBD that can be associated with high morbidity and mortality. This report is of a case of cerebral venous sinus thrombosis presenting in a young man during a relapse of ulcerative colitis (UC). CASE REPORT A 27-year-old man presented with seizures and focal neurological deficit during a relapse of chronic UC. He was found to have left cerebral venous sinus thrombosis complicated by left frontotemporal infarction that was treated with anticoagulation therapy. CONCLUSIONS Thromboembolic events are well documented extra-intestinal manifestation of IBD. Cerebral venous sinus thrombosis is a rare but serious complication that can be fatal. The correct diagnosis and timely management require a high degree of suspicion in patients with IBD who present with a new-onset headache, focal neurological symptoms, seizure, or altered mental status.
炎症性肠病（IBD）的肠外表现包括血栓栓塞事件，可表现为深静脉血栓形成、肺栓塞和脑静脉窦血栓形成。脑静脉窦血栓形成是IBD的一种罕见并发症，可伴有高发病率和死亡率。本报告是一例在溃疡性结肠炎（UC）复发期间出现脑静脉窦血栓形成的年轻男性病例。病例报告：一名27岁男性在慢性UC复发期间出现癫痫发作和局灶性神经功能缺损。他被发现患有左脑静脉窦血栓形成并伴有左额颞叶梗死，接受了抗凝治疗。结论：血栓栓塞事件是IBD有充分文献记载的肠外表现。脑静脉窦血栓形成是一种罕见但严重的并发症，可能致命。对于出现新发头痛、局灶性神经症状、癫痫发作或精神状态改变的IBD患者，正确的诊断和及时的处理需要高度怀疑。
