Begbie F D, Douglas C M, Finlay F, Montgomery J
Department of Otolaryngology - Head and Neck Surgery,Queen Elizabeth University Hospital,Glasgow,Scotland,UK.
Department of Palliative Medicine,Queen Elizabeth University Hospital,Glasgow,Scotland,UK.
J Laryngol Otol. 2019 Apr;133(4):313-317. doi: 10.1017/S0022215119000574. Epub 2019 Apr 1.
There is little consensus on how best to manage head and neck cancer with palliative intent. Predicting outcome is difficult and reported survival varies. The present study sought to delineate local practice and outcomes in patients treated with palliative intent.
The clinical records of all head and neck cancer patients treated with palliative intent presenting between 2015 and 2016 to our multidisciplinary team were reviewed.
Eighty-four patients (21.5 per cent) were treated with palliative intent. All had squamous cell carcinoma. Mean survival time was 151 days (standard deviation = 121.1; range, 8-536 days). Of the patients, 83.3 per cent had a palliative care referral; 74.1 per cent had a hospice referral. Patients received a variety of interventions, and there was an associated complication in 8.2 per cent. The mean number of days spent in hospital for interventions was 11.9 days (standard deviation = 12.5; range, 0-41 days).
Different interventions are used to manage head and neck cancer patients with palliative intent, and these may be associated with significant morbidity. Survival time is variable, often several months; thus, any treatment must take into account morbidity in conjunction with the patient's wishes.
对于如何以姑息治疗目的最佳管理头颈癌，目前几乎没有共识。预测结果很困难，且报道的生存率各不相同。本研究旨在描述接受姑息治疗的患者的当地治疗实践及结果。
回顾了2015年至2016年间向我们的多学科团队就诊的所有接受姑息治疗的头颈癌患者的临床记录。
84例患者（21.5%）接受了姑息治疗。所有患者均为鳞状细胞癌。平均生存时间为151天（标准差=121.1；范围8 - 536天）。其中，83.3%的患者接受了姑息治疗转诊；74.1%的患者接受了临终关怀转诊。患者接受了多种干预措施，8.2%出现了相关并发症。干预住院的平均天数为11.9天（标准差=12.5；范围0 - 41天）。
不同的干预措施用于以姑息治疗目的管理头颈癌患者，这些措施可能会导致显著的发病率。生存时间各不相同，通常为几个月；因此，任何治疗都必须结合患者意愿考虑发病率。
