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Infliximab biosimilar CT-P13 in Crohn's disease.

作者信息

Gecse Krisztina B, D'Haens Geert R

机构信息

Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, Netherlands.

Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, Netherlands.

出版信息

Lancet. 2019 Apr 27;393(10182):1671-1672. doi: 10.1016/S0140-6736(18)32778-8. Epub 2019 Mar 28.

DOI:10.1016/S0140-6736(18)32778-8
PMID:30929894
Abstract
摘要

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Infliximab biosimilar CT-P13 in Crohn's disease.英夫利昔单抗生物类似药CT-P13用于克罗恩病的治疗
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2
Efficacy and safety of biosimilar CT-P13 compared with originator infliximab in patients with active Crohn's disease: an international, randomised, double-blind, phase 3 non-inferiority study.比较 CT-P13 生物类似药与原研英夫利昔单抗治疗活动性克罗恩病患者的疗效和安全性:一项国际、随机、双盲、3 期非劣效性研究。
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Serum concentrations after switching from originator infliximab to the biosimilar CT-P13 in patients with quiescent inflammatory bowel disease (SECURE): an open-label, multicentre, phase 4 non-inferiority trial.在炎症性肠病处于缓解期的患者中,由原研英夫利昔单抗转换为生物类似药 CT-P13 后的血清浓度(SECURE):一项开放标签、多中心、四期非劣效性试验。
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Efficacy of the new infliximab biosimilar CT-P13 induction therapy in Crohn's disease and ulcerative colitis - experiences from a single center.新型英夫利昔单抗生物类似药CT-P13诱导治疗克罗恩病和溃疡性结肠炎的疗效——单中心经验
Expert Opin Biol Ther. 2015;15(9):1257-62. doi: 10.1517/14712598.2015.1064893. Epub 2015 Jul 2.
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Infliximab biosimilar CT-P13 therapy is effective and safe in maintaining remission in Crohn's disease and ulcerative colitis - experiences from a single center.英夫利昔单抗生物类似药CT-P13治疗在维持克罗恩病和溃疡性结肠炎缓解方面有效且安全——来自单一中心的经验
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Induction Therapy With Biosimilar Infliximab in Children With Crohn Disease.生物类似药英夫利昔单抗用于儿童克罗恩病的诱导治疗
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CT-P13 biosimilar is non-inferior to infliximab.
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Switching maintenance infliximab therapy to biosimilar infliximab in inflammatory bowel disease patients.在炎症性肠病患者中,将英夫利昔单抗维持治疗转换为英夫利昔单抗生物类似药治疗。
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Long-Term Clinical Outcomes After Switching from Remicade to Biosimilar CT-P13 in Inflammatory Bowel Disease.炎症性肠病患者从类克转换为生物类似药CT-P13后的长期临床结局
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Similar But Not Identical: Plaque Psoriasis Exacerbation in a Patient With Crohn's Disease After Switching From CT-P13 to SB2 Infliximab Biosimilar.相似但不相同:克罗恩病患者从CT-P13换用SB2英夫利昔单抗生物类似药后出现斑块状银屑病加重
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引用本文的文献

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Therapeutic regimen of Crohn's disease: effect of Infliximab combined with mesalazine on intestinal flora and inflammatory indexes in patients.克罗恩病的治疗方案:英夫利昔单抗联合美沙拉嗪对患者肠道菌群及炎症指标的影响
BMC Gastroenterol. 2025 Sep 29;25(1):687. doi: 10.1186/s12876-025-04236-9.
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Biosimilars to Antitumor Necrosis Factor Agents in Inflammatory Bowel Disease.炎症性肠病中抗肿瘤坏死因子药物的生物类似药
Biologics. 2020 Jan 10;14:1-11. doi: 10.2147/BTT.S236433. eCollection 2020.