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经导管弹簧圈栓塞治疗Ⅱ型肾动静脉畸形的疗效和安全性。

Efficacy and Safety of Transvenous Embolization of Type II Renal Arteriovenous Malformations with Coils.

机构信息

Department of Radiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

Department of Radiology, Samsung Medical Center and Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea.

出版信息

J Vasc Interv Radiol. 2019 Jun;30(6):807-812. doi: 10.1016/j.jvir.2018.09.019. Epub 2019 Mar 28.

Abstract

PURPOSE

To evaluate the efficacy and safety of transvenous coil embolization of the venous sac for type II renal arteriovenous malformation (AVM).

MATERIALS AND METHODS

A retrospective review was conducted of 8 patients (5 women and 3 men; mean age, 57 years; age range, 41-69 years) who underwent transvenous coil embolization for type II congenital renal AVM at 5 different hospitals between 2012 and 2018. Additional intra-arterial ethanol injection was performed if shunt flow persisted after venous sac coiling. Technical success was defined as complete occlusion of shunt flow with coil embolization. Clinical success was defined as no symptom recurrence during the follow-up period. The renal parenchymal infarction rate was measured on computed tomography (CT), and procedure-related complications were reviewed.

RESULTS

Nine sessions of embolization were performed for 8 patients. The mean venous sac size was 24 mm (range, 10-39 mm), and a mean of 14 micro and/or micro-detachable coils (range, 3-50) were used. The technical success rate was 88% (7 of 8) using coil embolization. One patient (12%) required additional ethanol injection to complete occlusion of the shunt flow and had a less than 10% parenchymal infarction on follow-up CT. No procedure-related complications or recurrences occurred during a mean clinical follow-up period of 20.8 months (range, 4.7-76.6 months).

CONCLUSIONS

Transvenous coil embolization of type II renal AVM showed an 88% technical success rate. One patient (12%) showed less than 10% renal parenchymal infarction after additional ethanol injection. No additional complications or recurrences occurred during the follow-up period.

摘要

目的

评估经静脉线圈栓塞治疗 II 型肾动静脉畸形(AVM)静脉囊的疗效和安全性。

材料与方法

回顾性分析了 2012 年至 2018 年间 5 家不同医院的 8 例(5 例女性,3 例男性;平均年龄 57 岁;年龄范围 41-69 岁)接受经静脉线圈栓塞治疗的 II 型先天性肾 AVM 患者。如果静脉囊线圈栓塞后分流仍存在,可追加经动脉乙醇注射。技术成功定义为通过线圈栓塞完全闭塞分流。临床成功定义为在随访期间无症状复发。通过计算机断层扫描(CT)测量肾实质梗死率,并回顾分析与操作相关的并发症。

结果

对 8 例患者进行了 9 次栓塞治疗。静脉囊平均大小为 24mm(范围 10-39mm),平均使用 14 枚微栓子和/或微可脱弹簧圈(范围 3-50 枚)。7 例(88%)患者通过线圈栓塞达到技术成功。1 例(12%)患者需要追加乙醇注射以完全闭塞分流,随访 CT 显示肾实质梗死小于 10%。平均 20.8 个月(范围 4.7-76.6 个月)的临床随访期间,未发生与操作相关的并发症或复发。

结论

经静脉线圈栓塞治疗 II 型肾 AVM 的技术成功率为 88%。1 例(12%)患者在追加乙醇注射后肾实质梗死小于 10%。随访期间未发生其他并发症或复发。

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