Bedotto J, Spier C M, Paquin M L, Grogan T M, Ahmann F R, Greenberg B R
Cancer. 1986 Nov 1;58(9):2125-9. doi: 10.1002/1097-0142(19861101)58:9<2125::aid-cncr2820580927>3.0.co;2-t.
A 68-year-old man with a 7-year history of lymphocytosis and lymphadenopathy is described. Accelerated disease, indicated by bilateral optic nerve and cerebrospinal fluid involvement, prompted thorough histologic and immunologic assessment. Although initially believed to have chronic lymphocytic leukemia (CLL), results showed mantle zone lymphoma (MZL) with central nervous system (CNS) involvement. The authors believe that this represents the first case of MZL with CNS involvement.
本文描述了一位68岁男性，其淋巴细胞增多和淋巴结病已有7年病史。双侧视神经和脑脊液受累提示疾病进展，促使进行了全面的组织学和免疫学评估。尽管最初认为患有慢性淋巴细胞白血病（CLL），但结果显示为伴有中枢神经系统（CNS）受累的套细胞淋巴瘤（MZL）。作者认为这是首例伴有CNS受累的MZL病例。
