Yoshimoto Y, Sakumoto T, Arai R, Miyake A, Kimura H, Aono T, Tanizawa O, Maeda T
Endocrinology. 1986 Oct;119(4):1800-4. doi: 10.1210/endo-119-4-1800.
A new coupled peroxidatic oxidation method for histochemical detection of monoamine oxidase (MAO) was applied to rat ovary. With this new method, fixed tissues could be used, and two forms of MAO could be identified by use of selective inhibitors. MAO activity was observed in the corpora lutea, interstitial gland cells, and blood vessels. In the corpora lutea, no activity was detected during the first estrous cycle, but strong activity was observed in the next two cycles. MAO in blood vessels showed characteristic changes of activity during the estrous cycle. The results suggest that MAO activity might possibly be involved in ovulation and progesterone metabolism in the ovary. Like other organs, rat ovary was found to contain two types of MAO; type A MAO was predominant in the corpora lutea. On the other hand, only one type of MAO, type B, was found in the blood vessels.
一种用于组织化学检测单胺氧化酶（MAO）的新型偶联过氧化物氧化方法应用于大鼠卵巢。采用这种新方法，可以使用固定组织，并且通过使用选择性抑制剂可以鉴定出两种形式的MAO。在黄体、间质腺细胞和血管中观察到MAO活性。在黄体中，在第一个发情周期未检测到活性，但在接下来的两个周期中观察到强烈活性。血管中的MAO在发情周期中表现出活性的特征性变化。结果表明，MAO活性可能参与卵巢中的排卵和孕酮代谢。与其他器官一样，发现大鼠卵巢含有两种类型的MAO；A型MAO在黄体中占主导地位。另一方面，在血管中仅发现一种类型的MAO，即B型。
