Department of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Department of Mental Health and Pathological Addiction, Azienda USL di Bologna, Bologna, Italy.
Suicide Life Threat Behav. 2019 Dec;49(6):1637-1652. doi: 10.1111/sltb.12549. Epub 2019 Apr 1.
Suicide risk in subjects at Ultra-High Risk of psychosis (UHR) has been rarely assessed in adolescence, but it is of obvious importance for prognostic and clinical care reasons. In this study, we aimed to prospectively assess suicide risk and behaviors in UHR adolescents.
We examined 112 help-seeking adolescents (13-18 years, 50% males, 83.9% Caucasian) that were enrolled in the Reggio Emilia At-Risk Mental States (ReARMS) project and followed up for 2 years. Specific items derived from the Comprehensive Assessment of At-Risk Mental States (CAARMS) and the Beck Depression Inventory-II (BDI-II) were used to assess suicide risk. Suicide attempts and completed suicides were also recorded.
Baseline assessment detected 40 UHR adolescents, 32 FEP (first-episode psychosis), and 40 non-UHR/FEP. We found that 67.5% of UHR adolescents had suicidal ideation, and 18.5% to severe degree. Attempted suicide before enrollment was higher in the UHR group than in non-UHR/FEP peers (17.5% vs. 2.5%). BDI-II suicidal ideation severity was stable at 12-month follow-up and decreased at 24-month follow-up.
A high prevalence of suicidal ideation among UHR adolescents was found and supports the routine monitoring of risk of self-injurious thinking and behavior in this at-risk population.
精神病超高风险（UHR）人群的自杀风险在青少年中很少被评估，但出于预后和临床护理的原因，这一点非常重要。本研究旨在前瞻性评估 UHR 青少年的自杀风险和行为。
我们检查了 112 名寻求帮助的青少年（13-18 岁，50%为男性，83.9%为白种人），他们参加了雷焦艾米利亚高危精神状态（ReARMS）项目，并随访了 2 年。使用源自高危精神状态综合评估（CAARMS）和贝克抑郁量表二（BDI-II）的特定项目来评估自杀风险。还记录了自杀企图和自杀完成情况。
基线评估发现 40 名 UHR 青少年、32 名首发精神病（FEP）和 40 名非 UHR/FEP。我们发现，67.5%的 UHR 青少年有自杀意念，18.5%为重度。在入组前，UHR 组的自杀未遂率高于非 UHR/FEP 同龄人（17.5%比 2.5%）。BDI-II 自杀意念严重程度在 12 个月随访时保持稳定，在 24 个月随访时降低。
发现 UHR 青少年自杀意念的患病率较高，这支持在高危人群中常规监测自我伤害思维和行为的风险。
