Gupta Tina, Antezana Ligia, Porter Christian, Mayanil Tushita, Bylsma Lauren M, Maslar Michael, Horton Leslie E
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
The Family Institute at Northwestern University, Evanston, IL, United States.
Front Psychiatry. 2023 Mar 2;14:1083368. doi: 10.3389/fpsyt.2023.1083368. eCollection 2023.
Intervention strategies for those diagnosed with psychotic disorders such as schizophrenia can be effective in reducing symptoms and improving quality of life. While strides have been made in developing prevention and intervention strategies earlier on in the disease progression, among those at clinical high-risk (CHR) for psychosis, challenges with heterogeneity can limit symptom and diagnosis specific treatment. Here, we discuss a newly developed therapy skills group called the Skills Program for Awareness, Connectedness, and Empowerment (SPACE) that integrates different types of behavioral skills - standard and radically open dialectical behavioral therapy as well as cognitive behavioral therapy - for CHR youth between the ages of 13-18 years. With the diathesis-stress framework serving as a foundation, the intervention is divided into three stages. These stages target specific signs and symptoms contributing to the progression of CHR symptoms. Stage 1 targets stress (with the goal of developing awareness and reducing distress), stage 2 targets self-disturbances (with a goal of increasing self-connectedness), and stage 3 targets social connectedness (with a goal of improving social domains of functioning). The focus of this article is to introduce the theoretical framework underlying the pilot skills group and discuss ongoing progress.
NCT05398120; https://clinicaltrials.gov/ct2/show/NCT05398120.
对于精神分裂症等被诊断患有精神障碍的患者,干预策略可有效减轻症状并改善生活质量。虽然在疾病进展的早期阶段制定预防和干预策略方面已取得进展,但在临床高危(CHR)精神病患者中,异质性带来的挑战可能会限制针对症状和诊断的特定治疗。在此,我们讨论一种新开发的治疗技能小组,称为意识、联系与赋权技能计划(SPACE),它整合了不同类型的行为技能——标准和激进开放辩证行为疗法以及认知行为疗法——用于13至18岁的CHR青少年。以素质-应激框架为基础,干预分为三个阶段。这些阶段针对导致CHR症状进展的特定体征和症状。第一阶段针对压力(目标是提高意识并减轻痛苦),第二阶段针对自我干扰(目标是增强自我联系),第三阶段针对社会联系(目标是改善社会功能领域)。本文的重点是介绍试点技能小组的理论框架并讨论进展情况。
NCT05398120;https://clinicaltrials.gov/ct2/show/NCT05398120 。