Krishnan Anoushka, Irani Khushnam, Swaminathan Ramyasuda, Boan Peter
a Department of Nephrology and Renal Transplantation , Royal Perth Hospital , Perth , Western Australia , Australia.
b Department of Nephrology and Renal Transplantation , Fiona Stanley Hospital , Perth Western Australia , Australia.
J Chemother. 2019 May;31(3):132-136. doi: 10.1080/1120009X.2019.1595894. Epub 2019 Apr 1.
Infection is a serious complication of tunnelled haemodialysis catheters. We aimed to describe the epidemiology of tunnelled haemodialysis central line-associated bloodstream infections (CLABSI) in an Australian centre. We performed a retrospective audit of tunnelled haemodialysis CLABSI from June 2010 to June 2014. From 674 catheter insertions, 70 CLABSI occurred in 55 patients at a rate of 0.95 infections per 1000 catheter days. Aboriginal and Torres Strait Islanders (ATSI) compared to non-ATSI had a higher rate of CLABSI (1.70 vs 0.58 CLABSI per 1000 catheter days, p < 0.001). Staphylococcus aureus (n = 22, 31.4%), coagulase negative Staphylococci (n = 14, 17.5%), and Gram negative bacilli (n = 28, 35.0%) were the predominant causative organisms. Two patients who died both had Staphylococcus aureus infection. In conclusion, our infection rate and microbiology are similar to prior reports. Morbidity and mortality are associated with Staphylococcus aureus as the causative organism.
感染是带隧道的血液透析导管的严重并发症。我们旨在描述澳大利亚一个中心带隧道的血液透析中心静脉导管相关血流感染（CLABSI）的流行病学情况。我们对2010年6月至2014年6月期间带隧道的血液透析CLABSI进行了回顾性审计。在674次导管插入操作中，55例患者发生了70例CLABSI，发生率为每1000导管日0.95次感染。与非原住民和托雷斯海峡岛民（ATSI）相比，原住民和托雷斯海峡岛民的CLABSI发生率更高（每1000导管日1.70次CLABSI对0.58次，p＜0.001）。金黄色葡萄球菌（n = 22，31.4%）、凝固酶阴性葡萄球菌（n = 14，17.5%）和革兰氏阴性杆菌（n = 28，35.0%）是主要的致病微生物。两名死亡患者均为金黄色葡萄球菌感染。总之，我们的感染率和微生物学情况与先前报告相似。发病率和死亡率与作为致病微生物的金黄色葡萄球菌有关。
