Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Complement Ther Med. 2019 Apr;43:300-305. doi: 10.1016/j.ctim.2019.02.002. Epub 2019 Feb 7.
The traditional uses of Portulaca oleracea L. (purslane) with anti-inflammatory and anti-cancer activity as well as anti-oxidants properties were expressed previously. This is a double-blind randomized clinical trial to evaluate the protective effects of purslane cream on the nipple fissure.
After expressing the goals and methods of the study and obtaining written consent from 86 lactating women with nipple fissure, they were randomly divided into two groups: 43 in purslane cream group and 43 in lanolin ointment group. The score of nipple fissure before the intervention and on the third and eighth day after the study was measured using the Stour scale.
The mean score of left and right breast fissures in the group of treatment with lanolin group similar to the group of treatment with purslane cream showed a significant decrease at the third day and eighth day (P=0.001). Mann-Whitney test comparing mean score of the fissure between two groups showed that two groups were homogeneous before the intervention, but there was a significant difference between two groups on the third and eighth days (p < 0.001). The recovery process occurred faster in the group of treatment with purslane cream.
We showed that the use of purslane cream without any complications could accelerate the repairing of nipple fissure. Based on this clinical trial, purslane cream (2% w/w) can be used as an accelerator for improving the nipple fissure in lactating women.
马齿苋(马齿苋)具有抗炎和抗癌作用以及抗氧化特性,其传统用途先前已经得到了表达。这是一项双盲随机临床试验,旨在评估马齿苋乳膏对乳头皲裂的保护作用。
在表达了研究的目标和方法并获得 86 名患有乳头皲裂的哺乳期妇女的书面同意后,将她们随机分为两组:马齿苋乳膏组 43 例,羊毛脂软膏组 43 例。采用 Stour 量表在干预前和研究第 3 天和第 8 天测量乳头皲裂评分。
使用羊毛脂组治疗的左侧和右侧乳房皲裂的平均评分与使用马齿苋乳膏组的治疗相似,第 3 天和第 8 天的评分明显下降(P=0.001)。Mann-Whitney 检验比较两组之间皲裂的平均评分表明,两组在干预前是同质的,但在第 3 天和第 8 天两组之间存在显著差异(p<0.001)。使用马齿苋乳膏治疗的组恢复过程更快。
我们表明,使用马齿苋乳膏不会引起任何并发症,可以加速乳头皲裂的修复。基于这项临床试验,2%(w/w)的马齿苋乳膏可作为加速哺乳期妇女乳头皲裂愈合的药物。