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腹腔镜子宫肌瘤剔除术后住院预测因素:高容量微创妇科手术环境。

Predictors of Overnight Admission After Laparoscopic Myomectomy in a High-Volume Minimally Invasive Gynecologic Surgery Setting.

机构信息

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, George Washington University, Washington, DC (Drs. Moawad and Maasen).

Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, George Washington University, Washington, DC (Dr. Park).

出版信息

J Minim Invasive Gynecol. 2020 Jan;27(1):195-199. doi: 10.1016/j.jmig.2019.03.022. Epub 2019 Mar 29.

Abstract

STUDY OBJECTIVE

Our primary goal was to uncover preoperative and intraoperative risk factors that prevented same-day discharge (SDD) after myomectomy in a setting where SDD was the standard of care. Uncovered predictors would serve to enhance patient counseling and medical optimization before surgery.

DESIGN

Single-center retrospective cohort study.

SETTING

Urban university hospital center, by fellowship-trained minimally invasive gynecologic surgeons.

PATIENTS

A total of 315 consecutive patients undergoing minimally invasive myomectomy between March 2012 and May 2018.

INTERVENTION

Minimally invasive myomectomy.

MEASUREMENTS AND MAIN RESULTS

Preoperative and intraoperative characteristics were collected for analysis as predictors of SDD vs overnight admission. Comparisons of demographic, clinical, imaging, and operative characteristics were made using appropriate statistical methods for normally distributed, skewed, and categorical variables. Length of stay was analyzed as a categorical variable, SDD vs overnight admission. A logistic regression model was used to evaluate SDD vs any overnight stay. Out of the 315 patients undergoing laparoscopic myomectomy, 208 (66.03%) were discharged on the same day, and 107 (33.96%) were admitted for at least 1 day after surgery. The patients were more likely to be admitted overnight if they were of Asian ethnicity (p = .01), or if they had a lower preoperative Hct (36.15 vs 37.57; p < .003). An increase in any myoma characteristic metric was associated with overnight stay after surgery; these included mean myoma weight (512.0 g vs 310.1 g; p < .001), estimated size of the largest myoma on imaging (9.01 cm vs 7.77 cm; p < .001), and number of myomas removed (6.59 vs 5.57; p = .021). Other statistically significant differences between the overnight admission and SDD groups were mean estimated blood loss (599.4 mL vs 221.9 mL; p < .001), operative time (224.4 minutes vs 140.9 minutes; p < .001), and surgery end time (15:02 hours vs 12:43 hours; p < .001). Intraoperative complications associated with overnight admission were estimated blood loss >1 L (p < .001) and any intraoperative transfusion (p < .001). The adjusted logistic regression model identified an increase in operative time (by 60 minutes) and later surgery end time (by 60 minutes) as predictors of an overnight stay, whereas an 5% increase in preoperative hematocrit was associated with a 34% decrease in odds for an overnight stay.

CONCLUSION

Perioperative factors, such as preoperative hematocrit, and myoma characteristics, as well as intraoperative factors, such as prolonged operative time and surgery end-time, are independent predictors of overnight hospital admission after minimally invasive myomectomy. Our present data can be used to provide better patient counseling before surgery.

摘要

研究目的

我们的主要目标是在微创子宫肌瘤剔除术标准治疗方案为当日出院(SDD)的环境下,找出术前和术中的风险因素,以避免这种情况。发现的预测因素将有助于在手术前增强患者咨询和医疗优化。

设计

单中心回顾性队列研究。

地点

由经过 fellowship 培训的微创妇科医生在城市大学医院中心进行。

患者

2012 年 3 月至 2018 年 5 月期间,共连续 315 例接受微创子宫肌瘤剔除术的患者。

干预措施

微创子宫肌瘤剔除术。

测量和主要结果

收集术前和术中特征作为 SDD 与过夜入院的预测因素进行分析。使用适当的统计方法对正态分布、偏态和分类变量进行比较。使用分类变量分析住院时间,即 SDD 与过夜入院。使用逻辑回归模型评估 SDD 与任何过夜住院的关系。在接受腹腔镜子宫肌瘤剔除术的 315 例患者中,208 例(66.03%)当天出院,107 例(33.96%)至少住院 1 天。如果患者是亚洲人(p = 0.01),或术前 Hct 较低(36.15 比 37.57;p < 0.003),则更有可能过夜入院。任何子宫肌瘤特征指标的增加与术后过夜住院有关;这些包括平均肌瘤重量(512.0 克比 310.1 克;p < 0.001)、影像学上最大肌瘤的估计大小(9.01 厘米比 7.77 厘米;p < 0.001)和切除的肌瘤数量(6.59 比 5.57;p = 0.021)。过夜入院组和 SDD 组之间的其他统计学差异包括平均估计出血量(599.4 毫升比 221.9 毫升;p < 0.001)、手术时间(224.4 分钟比 140.9 分钟;p < 0.001)和手术结束时间(15:02 小时比 12:43 小时;p < 0.001)。与过夜入院相关的术中并发症包括出血量超过 1 L(p < 0.001)和任何术中输血(p < 0.001)。调整后的逻辑回归模型确定手术时间增加 60 分钟(p < 0.001)和手术结束时间延迟 60 分钟(p < 0.001)是过夜住院的预测因素,而术前血细胞比容增加 5%与夜间住院的几率降低 34%相关。

结论

微创子宫肌瘤剔除术后的住院时间与围手术期因素(如术前血细胞比容和肌瘤特征)以及术中因素(如手术时间延长和手术结束时间延迟)有关。我们目前的数据可用于术前为患者提供更好的咨询。

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