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腹腔镜子宫肌瘤剔除术:治疗黏膜下子宫肌瘤的另一种方法?

Laparoscopic Myomectomy: An Alternative Approach to Tackling Submucous Myomas?

机构信息

Department of Women's Health, Whipps Cross Hospital, Barts Health NHS Trust, London, United Kingdom (Drs. Oxley and Odejinmi).

Department of Women's Health, Brighton and Sussex University Hospitals NHS Trust, Princess Royal Hospital, Haywards Heath, United Kingdom (Dr. Mallick).

出版信息

J Minim Invasive Gynecol. 2020 Jan;27(1):155-159. doi: 10.1016/j.jmig.2019.03.015. Epub 2019 Mar 26.

Abstract

STUDY OBJECTIVE

To evaluate the differences in perioperative outcomes and immediate complication rates between laparoscopic myomectomy for submucous myomas and laparoscopic myomectomy for myomas in other locations.

DESIGN

Retrospective cohort study.

SETTING

University-affiliated hospital in London.

PATIENTS

A total of 350 patients with symptomatic uterine myomas underwent laparoscopic myomectomy. Thirty-three of these were performed for submucous myomas (group 1), and 317 were for myomas in other uterine locations (group 2).

INTERVENTIONS

Analysis of prospectively collected data on patient demographics, myoma characteristics, perioperative outcomes, and immediate complications.

MEASUREMENTS AND MAIN RESULTS

Patient demographics, including age, body mass index, and parity, were similar in the 2 groups. No significant differences in myoma characteristics were seen between groups 1 and 2, including the mean dimension of largest myoma (7.1 vs 7.8 cm, respectively; p = .35), mean number of myomas removed (3.8 vs 4.1; p = .665), and mean mass of myomas removed (142.0 g vs 227.3 g; p = .186). There were also no significant between-group differences in any perioperative outcomes, including mean blood loss (226.8 mL vs 266.4 mL; p = .373), duration of surgery (103 minutes vs 113 minutes; p = .264), and duration of hospital stay (1.4 days vs 1.7 days; p = .057). No complications arose from laparoscopic resection of submucous myomas.

CONCLUSION

Laparoscopic myomectomy for submucous myomas has similar perioperative outcomes and immediate complications as laparoscopic myomectomy for other myomas and can be considered for large or type 2 submucous myomas.

摘要

研究目的

评估黏膜下子宫肌瘤的腹腔镜肌瘤切除术与其他部位子宫肌瘤的腹腔镜肌瘤切除术的围手术期结果和即刻并发症发生率的差异。

设计

回顾性队列研究。

设置

伦敦大学附属医院。

患者

共有 350 名患有症状性子宫肌瘤的患者接受了腹腔镜子宫肌瘤切除术。其中 33 例为黏膜下子宫肌瘤(第 1 组),317 例为其他子宫部位的子宫肌瘤(第 2 组)。

干预措施

分析前瞻性收集的患者人口统计学、肌瘤特征、围手术期结果和即刻并发症的数据。

测量和主要结果

两组患者的人口统计学特征,包括年龄、体重指数和产次,相似。第 1 组和第 2 组的肌瘤特征无显著差异,包括最大肌瘤的平均尺寸(分别为 7.1 厘米和 7.8 厘米;p=0.35)、切除的肌瘤数量(分别为 3.8 个和 4.1 个;p=0.665)和切除的肌瘤质量(分别为 142.0 克和 227.3 克;p=0.186)。两组在任何围手术期结果方面也没有显著差异,包括平均失血量(分别为 226.8 毫升和 266.4 毫升;p=0.373)、手术时间(分别为 103 分钟和 113 分钟;p=0.264)和住院时间(分别为 1.4 天和 1.7 天;p=0.057)。黏膜下子宫肌瘤的腹腔镜切除术没有并发症。

结论

腹腔镜下切除黏膜下子宫肌瘤的围手术期结果和即刻并发症与腹腔镜下切除其他部位的子宫肌瘤相似,对于较大或 2 型黏膜下子宫肌瘤,可以考虑使用这种方法。

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