海藻糖-6-磷酸磷酸酶对分生组织决定状态的控制与酶活性解耦。
Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity.
机构信息
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Agricultural Genetics Institute, Hanoi, Vietnam.
出版信息
Nat Plants. 2019 Apr;5(4):352-357. doi: 10.1038/s41477-019-0394-z. Epub 2019 Apr 1.
Abstract
Meristem fate is regulated by trehalose 6-phosphate phosphatases (TPPs), but their mechanism of action remains mysterious. Loss of the maize TPPs RAMOSA3 and TPP4 leads to reduced meristem determinacy and more inflorescence branching. However, analysis of an allelic series revealed no correlation between enzymatic activity and branching, and a catalytically inactive version of RA3 complements the ra3 mutant. Together with their nuclear localization, these findings suggest a moonlighting function for TPPs.
摘要
分生组织的命运由海藻糖 6-磷酸磷酸酶（TPPs）调控，但它们的作用机制仍不清楚。玉米 TPPs RAMOSA3 和 TPP4 的缺失导致分生组织确定性降低和更多花序分枝。然而，对一系列等位基因的分析表明，酶活性与分枝之间没有相关性，并且 RA3 的催化失活版本可以弥补 ra3 突变体。结合它们的核定位，这些发现表明 TPPs 具有兼职功能。
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