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肺癌患者应用膨体聚四氟乙烯补片行肺动脉重建的手术效果。

Surgical outcome of pulmonary artery reconstruction using the expanded polytetrafluoroethylene patch in patients with lung cancer.

机构信息

Department of Thoracic Surgery, National Hospital Organization Chiba Medical Center, 4-1-2 Tsubakimori, Chuo-ku, Chiba, 260-8606, Japan.

Department of Thoracic Surgery, Tokyo Women's Medical University, Yachiyo Medical Center, 477-96 Owada-shinden, Yachiyo, Chiba, 276-8524, Japan.

出版信息

Surg Today. 2019 Sep;49(9):778-784. doi: 10.1007/s00595-019-01803-y. Epub 2019 Apr 1.

DOI:10.1007/s00595-019-01803-y
PMID:30937633
Abstract

PURPOSE

Pulmonary artery reconstruction is sometimes utilized as an alternative to pneumonectomy in lung cancer surgery. We herein report our experience of pulmonary artery reconstruction using an expanded polytetrafluoroethylene (ePTFE) patch based on the surgical results and long-term outcome.

METHODS

Clinical records of lung cancer patients who underwent patch plasty were reviewed retrospectively.

RESULTS

Between 2003 and 2017, pulmonary artery patch plasty were performed in 21 patients [18 males, 3 females; mean age 65 (range 47-79) years]. Induction chemoradiotherapy was performed in three patients. Bronchoplasty was performed in five patients. The pathologic stages were stage I in 3 patients, stage II in 6 and stage III in 12. Pneumonectomy, lobectomy and segmentectomy were performed in 2, 18 and 1 patient, respectively. The left upper lobe was the most frequent origin of lung cancer (15 patients). There was no reconstruction-related morbidity or mortality. The overall survival rate at 5 years was 64.1% with a mean follow-up of 39.5 months, and the survival rates for N0-1 and N2-3 were 80.8% and 28.6%, respectively.

CONCLUSION

Patch angioplasty using the ePTFE sheet is a reliable procedure in radical surgery for lung cancer.

摘要

目的

在肺癌手术中,肺动脉重建有时可作为肺切除术的替代方法。我们在此报告了基于手术结果和长期结果,使用膨体聚四氟乙烯(ePTFE)补片进行肺动脉重建的经验。

方法

回顾性分析了接受补片成形术的肺癌患者的临床记录。

结果

2003 年至 2017 年间,21 例患者接受了肺动脉补片成形术[18 例男性,3 例女性;平均年龄 65(47-79)岁]。3 例患者接受了诱导化疗放疗。5 例患者行支气管成形术。病理分期为Ⅰ期 3 例,Ⅱ期 6 例,Ⅲ期 12 例。行全肺切除术、肺叶切除术和肺段切除术的患者分别为 2、18 和 1 例。左肺上叶是肺癌最常见的起源部位(15 例)。无重建相关并发症或死亡。5 年总生存率为 64.1%,平均随访 39.5 个月,N0-1 期和 N2-3 期的生存率分别为 80.8%和 28.6%。

结论

使用 ePTFE 片进行补片血管成形术是肺癌根治性手术中一种可靠的方法。

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Long-segment pulmonary artery resection to avoid pneumonectomy: long-term results after prosthetic replacement.长段肺动脉切除避免全肺切除术:人工血管置换的长期结果。
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Surgical Techniques and Long-Term Results of Pulmonary Artery Reconstruction in Patients With Lung Cancer.
肺癌患者肺动脉重建的手术技术及长期结果
Ann Thorac Surg. 2015 Oct;100(4):1196-202; discussion 1202. doi: 10.1016/j.athoracsur.2015.04.124. Epub 2015 Jul 21.
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J Cardiothorac Surg. 2013 Dec 1;8:219. doi: 10.1186/1749-8090-8-219.
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Thoracic and cardiovascular surgery in Japan during 2011: Annual report by The Japanese Association for Thoracic Surgery.2011年日本胸心血管外科:日本胸外科学会年度报告
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