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一例由……引起的皮肤利什曼病病例

A Case of Cutaneous Leishmaniasis Caused by .

作者信息

Sirekbasan Serhat, Polat Erdal, Kutlubay Zekayi, Engin Burhan

机构信息

İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi TÜBİTAK Biyoterapi Araştırma ve Geliştirme Laboratuvarı, İstanbul, Türkiye

İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Tıbbi Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye

出版信息

Turkiye Parazitol Derg. 2019 Mar 28;43(1):41-43. doi: 10.4274/tpd.galenos.2019.6022.

Abstract

is a disease that is transmitted via Phlebotomine sand flies. Two clinical forms of leishmaniasis are observed in humans: Visceral and cutaneous leishamniasis. The latter is very widespread in our country and may resolve by itself with scar formation. Whereas visceral leishmaniasis can be lethal if left untreated. Recently, molecular studies have shown that agents causing visceral leishmaniasis may cause cutaneous leishmaniasis and vice-versa.

A 34-year-old female patient from Kahramanmaraş was sent to the microbiology laboratory with a pre-diagnosis of leishmaniasis. The smear taken from the patient was stained with Giemsa and was viewed by using a light microscopy. The materials taken via swab were examined with Real Time PCR and High Resolution Melting Analysis (HRMA).

amastigotes were viewed by using microscopy and diagnosis was confirmed. Real Time PCR was positive for and HRMA showed that the agent was .

As our county has a bridging role between Asia and Europe, we should be aware of the recent epidemiological changes about infections. We wanted to present this case becasue the causative agent of cutaneous leishmaniasis was in this case and the disease resolved without treatment.

摘要

利什曼病是一种通过白蛉传播的疾病。在人类中观察到两种临床形式的利什曼病:内脏利什曼病和皮肤利什曼病。后者在我国非常普遍,可能会自行痊愈并形成疤痕。而内脏利什曼病如果不治疗可能会致命。最近,分子研究表明,导致内脏利什曼病的病原体可能会导致皮肤利什曼病,反之亦然。

一名来自加济安泰普的34岁女性患者被初步诊断为利什曼病后被送往微生物实验室。从患者身上采集的涂片用吉姆萨染色,并通过光学显微镜观察。通过拭子采集的材料用实时聚合酶链反应和高分辨率熔解分析(HRMA)进行检测。

通过显微镜观察到无鞭毛体,诊断得到证实。实时聚合酶链反应对[具体病原体名称1]呈阳性,高分辨率熔解分析表明病原体是[具体病原体名称1]。

由于我国在亚洲和欧洲之间起着桥梁作用,我们应该了解有关[具体病原体名称1]感染的近期流行病学变化。我们想介绍这个病例,因为在这个病例中皮肤利什曼病的病原体是[具体病原体名称1],并且该疾病未经治疗就痊愈了。

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