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造血干细胞移植受者和血液恶性肿瘤患者中 DNA 病毒、腺病毒、多瘤病毒和细小病毒 B19 的感染。

Infections with DNA Viruses, Adenovirus, Polyomaviruses, and Parvovirus B19 in Hematopoietic Stem Cell Transplant Recipients and Patients with Hematologic Malignancies.

机构信息

Division of Infectious Diseases and International Medicine, University of Minnesota, 420 Delaware Street SE, MMC250, Minneapolis, MN 55455, USA.

出版信息

Infect Dis Clin North Am. 2019 Jun;33(2):501-521. doi: 10.1016/j.idc.2019.02.005. Epub 2019 Mar 30.

Abstract

Infections due to adenovirus, polyomaviruses (BK and JC viruses), and parvovirus B19 may not be as common as infections due to other DNA viruses, such as cytomegalovirus in patients with hematological malignancies and the recipients of hematopoietic stem cell transplantation. However, these infections may result in life-threatening diseases that significantly impact patients' recovery, morbidity, and mortality. Treating physicians should be aware of the diseases associated with these viruses, the patient populations at increased risk for complications due to these infections, and the available diagnostic and therapeutic approaches.

摘要

腺病毒、多瘤病毒(BK 和 JC 病毒)和细小病毒 B19 引起的感染可能不像其他 DNA 病毒(如血液恶性肿瘤患者和造血干细胞移植受者中的巨细胞病毒)引起的感染那么常见。然而,这些感染可能导致危及生命的疾病,显著影响患者的康复、发病率和死亡率。治疗医生应该了解与这些病毒相关的疾病、因这些感染而并发症风险增加的患者人群以及可用的诊断和治疗方法。

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