Department of Pediatrics, School of Medicine, Iwate Medical University, Morioka, Japan.
Department of Pediatrics, School of Medicine, Iwate Medical University, Morioka, Japan,
Blood Purif. 2019;47 Suppl 2:74-80. doi: 10.1159/000496654. Epub 2019 Apr 3.
Background/ Aims: Owing to practical and technical developments, continuous renal replacement therapy (CRRT) has been administered even in critically ill neonates. In this study, the complications in CRRT for neonates were examined to establish a safe CRRT.
This retrospective study reviewed the clinical records of neonates who underwent CRRT at our neonatal intensive care unit between 2009 and 2017.
Eight neonates with a body weight of 1,462-3,288 g were treated by 70 CRRT sessions with blood priming. Intradialytic hypotension (IDH) was observed in 39 sessions (55.7%), most of which occurred soon after the start of the CRRT. Body temperature decreased in 48 sessions (70.5%), and thrombocytopenia during CRRT occurred 30 times (42.9%).
Complications during CRRT in neonates comprised IDH at the start of the CRRT, body temperature decline, and thrombocytopenia. These complications need to be analyzed for a safe neonatal CRRT.
由于实际和技术的发展，连续肾脏替代疗法（CRRT）甚至在危重新生儿中也得到了应用。本研究旨在探讨 CRRT 在新生儿中的并发症，以建立安全的 CRRT。
本回顾性研究分析了 2009 年至 2017 年期间在我院新生儿重症监护病房接受 CRRT 的新生儿的临床记录。
8 例体重为 1462-3288g 的新生儿共进行了 70 次血液预充的 CRRT 治疗。39 次（55.7%）发生了透析中低血压（IDH），大多数发生在 CRRT 开始后不久。48 次（70.5%）出现体温下降，30 次（42.9%）在 CRRT 期间发生血小板减少症。
新生儿 CRRT 期间的并发症包括 CRRT 开始时的 IDH、体温下降和血小板减少症。需要对这些并发症进行分析，以确保新生儿 CRRT 的安全性。
