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外科医生的困境:美容隆胸患者植入物相关感染的治疗

Surgeons' Dilemma: Treatment of Implant-Associated Infection in the Cosmetic Breast Augmentation Patient.

作者信息

Vasilakis Vasileios, Yamin Feras, Reish Richard G

机构信息

Plastic and Reconstructive Surgery, Long Island Plastic Surgical Group, 999 Franklin Avenue, Garden City, NY, 11530, USA.

Division of Plastic and Reconstructive Surgery, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY, 11554, USA.

出版信息

Aesthetic Plast Surg. 2019 Aug;43(4):905-909. doi: 10.1007/s00266-019-01369-7. Epub 2019 Apr 3.

Abstract

BACKGROUND

Augmentation mammaplasty is the most common plastic surgical procedure performed in the USA. The management of severe implant-associated infection is a challenge, and the traditional two-stage treatment is associated with significant limitations. The aim of this literature review is to provide a comprehensive analysis of all studies dealing with the management of severe infection or implant exposure following cosmetic breast augmentation.

METHODS

The PubMed and Cochrane databases were searched through February 2018 for studies on the management of severe infection and threatened or actual implant exposure following primary augmentation mammaplasty. Search terms used were "breast implant," "breast prosthesis," "breast augmentation," "breast augmentation complications," "infected implant," "implant salvage" and "implant exposure."

RESULTS

Five articles met inclusion criteria. There was inconsistency in the reporting of several key factors, such as the antibiotic regimens employed, culture sensitivities, time from diagnosis to treatment, implant characteristics, as well as the precise treatment of the capsule and pocket. A total of 58 implants were treated, of which 37 (63.8%) were exposed in the setting of infection and 21 (36.2%) were infected without exposure. One-stage implant salvage was employed in 31 implants and was successful in all. The capsular contracture rate with this approach was 6.5%. Antibiotic-alone, non-operative treatment was employed in the salvage of 22 implants, with success and capsular contracture rates of 77.3 and 13.6%, respectively. In the setting of severe periprosthetic infection in the absence of implant exposure, antibiotic-alone treatment was successful in the salvage of 13 out of 14 implants (92.9%).

CONCLUSIONS

The inconsistency and paucity of the data in the literature preclude definitive conclusions with regard to the optimal management of the threatened implant following augmentation mammaplasty. Given the excellent salvage rates in this setting, a more prominent role and liberal utilization of implant salvage are proposed.

LEVEL OF EVIDENCE IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

背景

隆乳术是美国最常见的整形手术。严重的植入物相关感染的处理是一项挑战,传统的两阶段治疗存在显著局限性。本文献综述的目的是对所有涉及美容隆乳术后严重感染或植入物外露处理的研究进行全面分析。

方法

检索了截至2018年2月的PubMed和Cochrane数据库,以查找关于初次隆乳术后严重感染以及有植入物外露风险或实际发生植入物外露的处理的研究。使用的检索词包括“乳房植入物”“乳房假体”“隆乳术”“隆乳术并发症”“感染的植入物”“植入物挽救”和“植入物外露”。

结果

五篇文章符合纳入标准。在一些关键因素的报告上存在不一致性,如所采用的抗生素方案、培养敏感性、从诊断到治疗的时间、植入物特征,以及对包膜和腔隙的精确处理。总共治疗了58个植入物,其中37个(63.8%)在感染情况下发生外露,21个(36.2%)发生感染但未外露。31个植入物采用了一期植入物挽救,全部成功。采用这种方法的包膜挛缩率为6.5%。22个植入物的挽救采用了单纯抗生素非手术治疗,成功率和包膜挛缩率分别为77.3%和13.6%。在假体周围严重感染且无植入物外露的情况下,14个植入物中有13个(92.9%)采用单纯抗生素治疗成功挽救。

结论

文献中数据的不一致性和匮乏使得关于隆乳术后有植入物外露风险的最佳处理无法得出明确结论。鉴于在此情况下的出色挽救率,建议植入物挽救发挥更突出的作用并更广泛地应用。

证据等级IV:本刊要求作者为每篇文章指定证据等级。有关这些循证医学评级的完整描述,请参阅目录或在线作者指南www.springer.com/00266

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