Riediger Michael D, Stride Devon, Coke Sarah E, Kurz Adrian Z, Duong Andrew, Ayeni Olufemi R
Division of Orthopaedic Surgery, Department of Surgery, Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada.
Department of Medicine, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
Curr Rev Musculoskelet Med. 2019 Jun;12(2):166-172. doi: 10.1007/s12178-019-09548-4.
We reviewed the recent literature to identify and summarize new research surrounding anterior cruciate ligament reconstruction (ACLR) with augmentation in the form of additional soft tissue procedures or biologic augmentation. Specifically, we wanted to review the failure rates of these procedures in both the primary and revision settings.
The databases Embase, PubMed, and Medline were searched on August 13, 2018, for English-language studies that reported on the use of anterior cruciate ligament reconstruction (primary and revision) in conjunction with either soft tissue or biologic augmentation. The studies were systematically screened and data abstracted in duplicates.
Advancements in ACLR surgery, including soft tissue augmentation, may decrease primary and revision surgery failure rates for high-risk patients. The use of biological augmentation has shown histologic and radiographic improvements. These differences, however, have failed to be statistically significant and have not resulted in clinically significant improvements in outcome. The limited body of evidence has shown that the addition of soft tissue procedures may in fact lower the risk of graft re-rupture rates particularly in revision or in patients wishing to return to high-risk sports and activities. The use of biologic augmentation although promising in laboratory studies has yet to show any significant clinical results and therefore will require further studies to prove any efficacy.
我们回顾了近期文献,以识别和总结围绕前交叉韧带重建(ACLR)并采用额外软组织手术或生物增强形式进行增强的新研究。具体而言,我们想回顾这些手术在初次和翻修手术中的失败率。
2018年8月13日在Embase、PubMed和Medline数据库中检索了报道前交叉韧带重建(初次和翻修)联合软组织或生物增强使用情况的英文研究。对这些研究进行系统筛选,并由两人重复提取数据。
ACLR手术的进展,包括软组织增强,可能会降低高危患者初次和翻修手术的失败率。生物增强的使用已显示出组织学和影像学改善。然而,这些差异在统计学上并不显著,也未在临床结果上带来显著改善。有限的证据表明,增加软组织手术实际上可能会降低移植物再次断裂的风险,特别是在翻修手术中或对于希望恢复高危运动和活动的患者。生物增强尽管在实验室研究中有前景,但尚未显示出任何显著的临床结果,因此需要进一步研究来证明其疗效。