Klenka H M
Br Med J (Clin Res Ed). 1986 Sep 20;293(6549):745-6. doi: 10.1136/bmj.293.6549.745.
The effect of maternal abuse of heroin on newborn babies was studied in 25 babies born during 1982-6 to 23 heroin users, most of whom smoked the drug. Nineteen of the babies developed withdrawal symptoms, which in 12 were severe enough to require treatment. Five babies were born prematurely; 17 were adequately grown for their gestational age. Four mothers successfully established breast feeding. Twenty two infants were discharged from the hospital into their mother's care with support from the family and community services; at the end of the study only six were living in families in which the parents were married or had a stable relationship. Withdrawal symptoms were short lasting and often self limiting, and no evidence of adverse effect on postnatal growth and development was found. Unstable social circumstances with changes in family dynamics made follow up difficult. Further assessment needs to be carried out to investigate the long term effect of maternal heroin abuse on children.
对1982年至1986年间出生的25名新生儿进行了研究,其母亲为23名海洛因使用者,其中大多数吸食该毒品。19名婴儿出现了戒断症状,其中12名症状严重到需要治疗。5名婴儿早产;17名婴儿的生长发育与孕周相符。4名母亲成功进行了母乳喂养。22名婴儿在家庭和社区服务的支持下出院由母亲照料;研究结束时,只有6名婴儿生活在父母已婚或关系稳定的家庭中。戒断症状持续时间短且往往会自行缓解,未发现对出生后生长发育有不良影响的证据。家庭动态变化导致的不稳定社会环境使得随访困难。需要进一步评估以调查母亲滥用海洛因对儿童的长期影响。