Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Republic of Korea.
J Clin Psychiatry. 2019 Apr 2;80(3):17m12088. doi: 10.4088/JCP.17m12088.
High rates of childhood trauma and adult suicidality have been reported in patients who have schizophrenia. This study sought to explore mediators between childhood trauma and suicidality in adulthood to help determine therapeutic approaches.
This study included 314 adult patients with early psychosis who were participants in the Korean Early Psychosis Cohort Study, which was a prospective naturalistic observational cohort study started in December 2014. DSM-5 criteria were used to assign the diagnosis of schizophrenia spectrum and other psychotic disorders. Cross-sectional data obtained at baseline were used for analysis. The Early Trauma Inventory Self Report-Short Form and the Columbia Suicide Severity Rating Scale were employed to collect data on childhood trauma and suicidal ideation and attempts. Other measures were used to evaluate depression, empathy, psychopathology, and rumination.
A total of 90.1% of the participants experienced at least 1 childhood traumatic event. The rates of significant` physical punishment, emotional abuse, and sexual events were 37.3%, 35.6%, and 6.4%, respectively. The rates of recent suicidal ideation and attempts were 32.0% and 10.0%, respectively. Independent predictors of recent suicidal ideation included depression, negative schema, and rumination. Furthermore, negative schema and rumination played partial or full mediating roles in the relationship between childhood trauma and recent suicidal ideation.
These findings highlight the importance of performing careful evaluations of childhood trauma and suicidality and of developing effective strategies to reduce mediating factors that may be amenable to psychosocial approaches.
大量研究报告称,患有精神分裂症的患者童年期创伤和成年自杀率较高。本研究旨在探索童年期创伤与成年期自杀之间的中介因素,以帮助确定治疗方法。
本研究纳入了 314 名早期精神病患者,他们均为韩国早期精神病队列研究的参与者,该研究是一项始于 2014 年 12 月的前瞻性自然观察队列研究。采用 DSM-5 标准诊断精神分裂症谱系及其他精神病性障碍。分析采用基线时获得的横断面数据。采用早期创伤量表自我报告简表和哥伦比亚自杀严重程度评定量表收集童年期创伤和自杀意念及尝试的数据。其他评估方法用于评估抑郁、共情、精神病理学和反刍。
共有 90.1%的参与者经历过至少 1 次童年期创伤事件。遭受过严重身体惩罚、情感虐待和性事件的比例分别为 37.3%、35.6%和 6.4%。最近有自杀意念和尝试自杀的比例分别为 32.0%和 10.0%。最近有自杀意念的独立预测因素包括抑郁、消极图式和反刍。此外,消极图式和反刍在童年期创伤与最近自杀意念之间的关系中起部分或完全中介作用。
这些发现强调了仔细评估童年期创伤和自杀的重要性,以及制定有效策略减少可能适合心理社会方法的中介因素的重要性。