Jahn Klaus
Adv Otorhinolaryngol. 2019;82:143-149. doi: 10.1159/000490283. Epub 2019 Jan 15.
Aging in vestibular structures with loss of hair cells in the inner ear starts early in life, but vestibular function usually remains relatively unimpaired up to advanced ages. However, dizziness and imbalance are common in the elderly and have substantial impact on the quality of life. Dizziness interferes with the everyday activities of 30% of persons over age 70. As causes can be multiple, including vestibular and non-vestibular components, it is crucial to detect the factors leading to dizziness and imbalance to maintain mobility and avoid secondary complications like falls and anxiety. The more common causes of dizziness and imbalance in old age are sensory deficits, such as bilateral vestibular hypofunction, polyneuropathy, and impaired visual acuity; benign paroxysmal positional vertigo; and central disorders such as cerebellar ataxia and normal-pressure hydrocephalus. Further relevant factors include sedative or antihypertensive medication, loss of muscle mass (sarcopenia), and the fear of falling. Many elderly persons have multiple risk factors at the same time. Treatable components include benign paroxysmal positional vertigo that can be effectively treated with specific physical maneuvers, sedating drugs that can be reduced in many cases, and sarcopenia that can be treated with physical training. If a specific cause for dizziness and imbalance can be identified, treatment is often successful even in advanced age. The common causes can be revealed by systematic clinical examination and selective laboratory testing.
内耳毛细胞缺失导致的前庭结构衰老在生命早期就开始了,但前庭功能通常在高龄之前仍相对未受损害。然而,头晕和平衡失调在老年人中很常见,并且对生活质量有重大影响。头晕会干扰30%的70岁以上老人的日常活动。由于病因可能是多方面的,包括前庭和非前庭因素,因此检测导致头晕和平衡失调的因素对于维持活动能力以及避免跌倒和焦虑等继发并发症至关重要。老年人头晕和平衡失调更常见的原因是感觉缺陷,如双侧前庭功能减退、多发性神经病和视力受损;良性阵发性位置性眩晕;以及中枢性疾病,如小脑共济失调和正常压力脑积水。其他相关因素包括镇静或降压药物、肌肉量减少(肌肉减少症)以及跌倒恐惧。许多老年人同时存在多种危险因素。可治疗的因素包括可通过特定物理手法有效治疗的良性阵发性位置性眩晕、在许多情况下可减少使用的镇静药物以及可通过体育锻炼治疗的肌肉减少症。如果能够确定头晕和平衡失调的具体原因,即使在高龄患者中治疗往往也会取得成功。通过系统的临床检查和选择性实验室检测可以揭示常见病因。