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继发于核周型抗中性粒细胞胞浆抗体血管炎的孤立性睫状视网膜动脉阻塞。

Isolated cilioretinal artery occlusion secondary to perinuclear antineutrophil cytoplasmic antibody vasculitis.

作者信息

Mammo Danny A, McClelland Collin M, Chen John, Adams Matthew K, Pulido Jose, Davies John B

机构信息

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.

Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA.

出版信息

Eur J Ophthalmol. 2020 Sep;30(5):NP53-NP57. doi: 10.1177/1120672119841541. Epub 2019 Apr 5.

DOI:10.1177/1120672119841541
PMID:30947529
Abstract

INTRODUCTION

Antineutrophil cytoplasm antibody-associated vasculitides encompass a diverse spectrum of autoimmune diseases characterized by necrotizing small vessel vasculitis. Ocular manifestations may be the presenting findings of antineutrophil cytoplasm antibody-associated vasculitides.

METHODS

Single, retrospective case study.

RESULTS

We report the rare case of a 55-year-old woman with a cilioretinal artery occlusion as the presenting feature of perinuclear antineutrophil cytoplasm antibody-associated microscopic polyangiitis.

CONCLUSIONS

Although rare, antineutrophil cytoplasm antibody-related vasculitis should be considered in any retinal vascular occlusion, particularly in the setting of patients with new vague headaches and a paucity of vasculopathic risk factors.

摘要

引言

抗中性粒细胞胞浆抗体相关血管炎涵盖了一系列以坏死性小血管炎为特征的自身免疫性疾病。眼部表现可能是抗中性粒细胞胞浆抗体相关血管炎的首发症状。

方法

单例回顾性病例研究。

结果

我们报告了一例罕见病例,一名55岁女性以睫状视网膜动脉阻塞为核周抗中性粒细胞胞浆抗体相关显微镜下多血管炎的首发特征。

结论

尽管罕见,但在任何视网膜血管阻塞的情况下,尤其是伴有新发模糊头痛且血管病变危险因素较少的患者中,都应考虑抗中性粒细胞胞浆抗体相关血管炎。

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Eur J Ophthalmol. 2020 Sep;30(5):NP53-NP57. doi: 10.1177/1120672119841541. Epub 2019 Apr 5.
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