Reneflot Anne, Kaspersen Silje L, Hauge Lars Johan, Kalseth Jorid
Mental and Physical Health, Norwegian Institute of Public Health, PO Box 222, 0213, Skøyen, Oslo, Norway.
SINTEF Digital, Department of Health, The Norwegian University of Science and Technology, Trondheim, Norway.
BMC Health Serv Res. 2019 Apr 4;19(1):215. doi: 10.1186/s12913-019-4009-1.
The use of psychotropic medications in relation to mental disorders is considered central to preventing suicide. However, few studies have addressed prescription patterns at different time points within the last year prior to suicide and compared these with those of the general population.
We use data covering the period from 2010 to 2011 from the Norwegian Cause of Death Registry and the Norwegian Prescription Database to examine dispensing patterns of prescription medication within 12 months and within 30 days of suicide. Our data includes all registered suicides in Norway among individuals aged 15 years and older in 2011 (n = 594), 434 men and 160 women. Dispensing of prescription medication in the general population (n ≈ 4 million) are used for comparison.
Dispensing of any prescription medication were high and varied from 95.6% for females and 83.2% for males within 12 months of suicide, to 64.4% for females and 47.2% for males within 30 days of suicide, respectively. The percentages with dispensed prescription medication increased with age. A similar sex and age pattern was observed for the dispensing of psychotropic medications. Within the last 30 days, close to one in two were dispensed psychotropic medications. The dispensing of antidepressants, hypnotics and sedatives was more common than the dispensing of other categories of psychotropics. The percentages with dispensed prescription medication among the population controls were considerably lower, in particular the dispensing of psychotropics.
Dispensing of prescription medications, including psychotropic medications, is common prior to suicide. The percentage with dispensed prescription medication increases with age and are higher for females than for males.
使用精神药物治疗精神障碍被认为是预防自杀的核心措施。然而，很少有研究探讨自杀前一年不同时间点的处方模式，并将其与普通人群的处方模式进行比较。
我们使用来自挪威死亡原因登记处和挪威处方数据库的2010年至2011年期间的数据，研究自杀前12个月内和30天内处方药的配药模式。我们的数据包括2011年挪威15岁及以上人群中所有登记的自杀案例（n = 594），其中434名男性和160名女性。普通人群（n ≈ 400万）的处方药配药情况用于比较。
任何处方药的配药率都很高，自杀前12个月内女性为95.6%，男性为83.2%，自杀前30天内女性为64.4%，男性为47.2%。配药的处方药百分比随年龄增长而增加。在精神药物的配药方面也观察到类似的性别和年龄模式。在最后30天内，近二分之一的人配了精神药物。抗抑郁药、催眠药和镇静剂的配药比其他类别的精神药物更常见。人群对照组中配药的处方药百分比要低得多，尤其是精神药物的配药。
自杀前使用处方药，包括精神药物，很常见。配药的处方药百分比随年龄增长而增加，女性高于男性。
