Dewan Palki, Bhat Shubha P, Kishan Prasad H L, Ballal Rajesh, Sajitha K
K.S. Hegde Medical Academy, NITTE - Deemed to be University, Mangalore, Karnataka 575018 India.
Indian J Surg Oncol. 2019 Mar;10(1):199-203. doi: 10.1007/s13193-018-0834-7. Epub 2018 Dec 7.
Neuroendocrine carcinoma rarely occurs in the duodenum, and most cases of neuroendocrine carcinoma in the duodenum show rapid progression of the disease. Such cases have poor prognosis even with radical surgery with or without chemotherapy with low 5-year survival rate. We present a case of a 52-year-old man who presented with abdominal pain of 1-month duration and one episode of vomiting. Upper gastrointestinal endoscopy revealed polypoidal lesions in the first and second part of the duodenum. Whipple's procedure was performed. Diagnosis of poorly differentiated neuroendocrine carcinoma was made with extension to pancreas with peripancreatic lymph node metastases. The patient expired on post operative day 17 following cardiac arrest.
神经内分泌癌很少发生于十二指肠，十二指肠神经内分泌癌的大多数病例疾病进展迅速。即使接受了根治性手术（无论是否化疗），这些病例的预后也很差，5年生存率很低。我们报告一例52岁男性患者，其出现了持续1个月的腹痛和一次呕吐。上消化道内镜检查发现十二指肠第一部和第二部有息肉样病变。施行了胰十二指肠切除术。诊断为低分化神经内分泌癌，已侵犯胰腺并伴有胰周淋巴结转移。患者在术后第17天因心脏骤停死亡。
