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Transfusion. 2018 Dec;58(12):2819-2824. doi: 10.1111/trf.14932. Epub 2018 Oct 13.
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ACOG Practice Bulletin No. 192: Management of Alloimmunization During Pregnancy.美国妇产科医师学会临床实践公告第 192 号：孕期同种免疫的管理。
Obstet Gynecol. 2018 Mar;131(3):e82-e90. doi: 10.1097/AOG.0000000000002528.
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Persistent Pulmonary Hypertension of the Newborn.新生儿持续性肺动脉高压
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Persistent pulmonary hypertension of the newborn associated with severe congenital anemia of various etiologies.与各种病因引起的严重先天性贫血相关的新生儿持续性肺动脉高压。
J Pediatr Hematol Oncol. 2015 Jan;37(1):60-2. doi: 10.1097/MPH.0000000000000064.
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Persistent pulmonary hypertension of non cardiac cause in a neonatal intensive care unit.新生儿重症监护病房中由非心脏原因引起的持续性肺动脉高压
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Risk factors for persistent pulmonary hypertension of the newborn.新生儿持续性肺动脉高压的危险因素。
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一名患有抗-E同种免疫的新生儿出现胎儿水肿和持续性肺动脉高压

Hydrops Fetalis and Persistent Pulmonary Hypertension in a Neonate with Anti-E Alloimmunization.

作者信息

Sharma Amit, Navalkele Pournima, Desai Jagdish, Agarwal Prashant

机构信息

Department of Neonatal-Perinatal, Children's Hospital of Michigan, Neonatal-Perinatal Medicine, Detroit, MI, USA.

Department of Pediatrics, SSM Health Cardinal Glennon Children's Hospital, Hematology/Oncology, St. Louis, MO, USA.

出版信息

Case Rep Obstet Gynecol. 2019 Mar 4;2019:3736870. doi: 10.1155/2019/3736870. eCollection 2019.

DOI:10.1155/2019/3736870
PMID:30949372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6425396/
Abstract

Anti-E alloimmunization is the third most common cause of neonatal hemolytic disease, typically causing mild to moderate hemolytic anemia. We report an unusual case of severe hydrops fetalis and persistent pulmonary hypertension (PPHN) in a neonate with anti-E alloimmunization. Our case emphasizes the importance of close surveillance for development of severe fetal hemolytic anemia and possible need for antenatal intervention. These neonates may also need vigilant monitoring for PPHN.

摘要

抗-E同种免疫是新生儿溶血病的第三大常见病因，通常会导致轻度至中度溶血性贫血。我们报告了一例抗-E同种免疫新生儿发生严重胎儿水肿和持续性肺动脉高压（PPHN）的罕见病例。我们的病例强调了密切监测严重胎儿溶血性贫血发展情况以及可能需要进行产前干预的重要性。这些新生儿还可能需要对PPHN进行密切监测。